PAK6

Description		p21 (RAC1) activated kinase 6
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GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm Cell Junction
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Learning Memory Locomotory Behavior Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Neuron Projection Arborization Neuron Projection Extension
Pathways		Activation of RAC1
Drugs		Fostamatinib
Diseases
GWAS		Obesity-related traits ( 23251661) Schizophrenia ( 25056061 29483656) Weight gain in amisulpride-treated first-episode psychosis ( 32126890)
Novel Interacting Genes		8 novel interacting genes: CACNA1H CDIN1 DLL4 GJD2 KNL1 SP3 SPG11 SUMO2
Interacting Genes		20 interacting genes: APP AR CDC42 CDK1 DAPK1 ESR1 FBXO7 HSF2BP LIMK1 LRRK1 MAPK14 MDM2 NEK6 PTPRD RAC1 RHOJ RHOV SEMA3B SNX2 TPD52L1
Entrez ID		56924
HPRD ID		06426
Ensembl ID		ENSG00000137843
Uniprot IDs		A0A024R9Q4 Q9NQU5
PDB IDs		2C30 2ODB 4KS7 4KS8 6QDR 6QDS
Enriched GO Terms of Interacting Partners?
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