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SIRT7
Description
sirtuin 7
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Nucleolus Organizer Region
Cytoplasm
Nuclear Speck
Site Of Double-strand Break
Molecular Function
Chromatin Binding
Transcription Corepressor Activity
Histone Deacetylase Activity
Protein Binding
Deacetylase Activity
NAD-dependent Protein Deacetylase Activity
Protein-succinyllysine Desuccinylase Activity
Metal Ion Binding
Protein-glutaryllysine Deglutarylase Activity
NAD+ Binding
NAD-dependent Histone Deacetylase Activity (H3-K18 Specific)
Protein-propionyllysine Depropionylase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Regulation Of Gluconeogenesis
DNA Repair
Regulation Of DNA Repair
Protein Deacetylation
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Transcription Involved In Exit From Mitosis
Homologous Chromosome Pairing At Meiosis
RRNA Transcription
Negative Regulation Of Transposition
Regulation Of Mitochondrion Organization
Histone Modification
Negative Regulation Of Protein Ubiquitination
Peptidyl-lysine Desuccinylation
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Protein Export From Nucleus
Protein Deglutarylation
Peptidyl-lysine Deglutarylation
R-loop Disassembly
Histone H3 Deacetylation
Histone H4 Deacetylation
Protein Depropionylation
Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Histone Glutamine Methylation
Positive Regulation Of RRNA Processing
Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Drugs
Diseases
GWAS
Interacting Genes
12 interacting genes:
APP
DDB1
FBL
H2AC20
H2BC21
H3C1
H4C1
MAGED1
POLR1E
RRP9
USP7
WDR77
Entrez ID
51547
HPRD ID
12094
Ensembl ID
ENSG00000187531
Uniprot IDs
Q9NRC8
PDB IDs
5IQZ
6G0S
Enriched GO Terms of Interacting Partners
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