TMEM14C and VSIR

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM14C	VSIR
Description		transmembrane protein 14C	V-set immunoregulatory receptor
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Enzyme Binding Identical Protein Binding Endopeptidase Activator Activity
	Biological Process	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Regulation Of Heme Biosynthetic Process	Positive Regulation Of Gene Expression Positive Regulation Of Endopeptidase Activity Positive Regulation Of Cell Migration Zymogen Activation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Regulatory T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Collagen Catabolic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		46 interacting genes: ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SDC3 SHANK3 SLC10A6 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27	27 interacting genes: APOD ASGR1 ATP6V0C BMP10 C14orf180 CCL4L2 CLEC7A CLRN2 CNIH3 DOLK MS4A13 PLPP6 PLPPR2 PLSCR1 SLC35B1 SLC35B4 SMAD3 SMCO4 TMEM100 TMEM14C TMEM218 TMEM229B TMEM97 TNF TSPAN2 TSPO2 VAMP3
Entrez ID		51522	64115
HPRD ID		15524	15160
Ensembl ID		ENSG00000111843	ENSG00000107738
Uniprot IDs		A0A024R001 Q9P0S9	Q9H7M9
PDB IDs		2LOS	6MVL 6OIL 6U6V
Enriched GO Terms of Interacting Partners?
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