VSIR and CLRN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VSIR	CLRN2
Description		V-set immunoregulatory receptor	clarin 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Integral Component Of Membrane Stereocilium Bundle
	Molecular Function	Protein Binding Enzyme Binding Identical Protein Binding Endopeptidase Activator Activity	Protein Binding
	Biological Process	Positive Regulation Of Gene Expression Positive Regulation Of Endopeptidase Activity Positive Regulation Of Cell Migration Zymogen Activation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Regulatory T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Collagen Catabolic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation	Sensory Perception Of Sound Inner Ear Auditory Receptor Cell Differentiation Stereocilium Maintenance
Pathways
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		27 interacting genes: APOD ASGR1 ATP6V0C BMP10 C14orf180 CCL4L2 CLEC7A CLRN2 CNIH3 DOLK MS4A13 PLPP6 PLPPR2 PLSCR1 SLC35B1 SLC35B4 SMAD3 SMCO4 TMEM100 TMEM14C TMEM218 TMEM229B TMEM97 TNF TSPAN2 TSPO2 VAMP3	13 interacting genes: ARL6IP6 CLDN5 CLEC2D FNDC9 KLRC1 LRRC25 NEMP1 SIT1 SSMEM1 STOM TAPT1 TEX29 VSIR
Entrez ID		64115	645104
HPRD ID		15160	19335
Ensembl ID		ENSG00000107738	ENSG00000249581
Uniprot IDs		Q9H7M9	A0PK11
PDB IDs		6MVL 6OIL 6U6V
Enriched GO Terms of Interacting Partners?
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