TMEM14C and KASH5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TMEM14C	KASH5
Description		transmembrane protein 14C	KASH domain containing 5
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane	Chromosome, Telomeric Region Lateral Element Nuclear Outer Membrane Integral Component Of Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Dynein Complex Binding
	Biological Process	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Regulation Of Heme Biosynthetic Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Homologous Chromosome Pairing At Meiosis Spermatogenesis Telomere Localization Oogenesis Spindle Assembly Spindle Localization Microtubule Cytoskeleton Organization Involved In Homologous Chromosome Segregation Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Pathways
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		46 interacting genes: ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SDC3 SHANK3 SLC10A6 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27	112 interacting genes: ABHD1 ADIPOQ ANKRD46 ATF7 BAG5 BCL2L2 BET1 C14orf180 CCDC120 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CMTM5 CRABP2 CTXN3 CWF19L2 CXCL16 CXCL9 CYBC1 DERL1 DNAJC30 EFNA5 EMD FAM161A FAM241B FAM50B FAM90A1 FATE1 FIS1 FRA10AC1 FTCD FXYD3 GABARAPL2 GALNT2 GIMAP5 GOSR2 GPATCH4 GPR25 HMOX1 ITGAM ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA LRCH4 MALL MARCHF2 MFSD5 MMP14 MOSPD3 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PGAP2 PGRMC1 PIGU PLP2 PLPP6 PPP1R18 RIPPLY2 RNF146 RSPH14 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC35B4 SLC41A1 SLC41A2 SLC5A4 SLN SMCO4 SNAP47 STBD1 STX12 STX5 TCF25 TMEM11 TMEM147 TMEM14C TMEM19 TMEM199 TMEM41A TMEM86A TMPRSS4 TNF TRAF3IP3 TRARG1 TSHZ3 TTC23 UPK1B UPK2 VAMP1 VAMP2 VAMP4 VTI1B ZC2HC1C ZFPL1 ZNF250
Entrez ID		51522	147872
HPRD ID		15524	08134
Ensembl ID		ENSG00000111843	ENSG00000161609
Uniprot IDs		A0A024R001 Q9P0S9	Q8N6L0
PDB IDs		2LOS	6R2I 6WMF
Enriched GO Terms of Interacting Partners?
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