TMEM14C and MARCHF8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM14C	MARCHF8
Description		transmembrane protein 14C	membrane associated ring-CH-type finger 8
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane	Cytoplasm Lysosome Lysosomal Membrane Endosome Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding MHC Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Regulation Of Heme Biosynthetic Process	Protein Polyubiquitination Adaptive Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response
Pathways
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		46 interacting genes: ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SDC3 SHANK3 SLC10A6 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27	11 interacting genes: ARR3 CD86 CYB5B FA2H GOSR2 IL1RAP TMEM14C UBE2D1 UBE2D3 UBE2H VAMP2
Entrez ID		51522	220972
HPRD ID		15524	17466
Ensembl ID		ENSG00000111843	ENSG00000165406
Uniprot IDs		A0A024R001 Q9P0S9	A0A024R7U2 Q5T0T0
PDB IDs		2LOS	2D8S
Enriched GO Terms of Interacting Partners?
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