VSIR and SLC35B4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VSIR	SLC35B4
Description		V-set immunoregulatory receptor	solute carrier family 35 member B4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Enzyme Binding Identical Protein Binding Endopeptidase Activator Activity	UDP-N-acetylglucosamine Transmembrane Transporter Activity UDP-xylose Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity
	Biological Process	Positive Regulation Of Gene Expression Positive Regulation Of Endopeptidase Activity Positive Regulation Of Cell Migration Zymogen Activation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Regulatory T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Collagen Catabolic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation	Regulation Of Gluconeogenesis Carbohydrate Transport UDP-xylose Transmembrane Transport UDP-N-acetylglucosamine Transmembrane Transport
Pathways			Transport of nucleotide sugars
Drugs
Diseases
GWAS			Mean platelet volume ( 32888494 27863252) Plateletcrit ( 32888494) Systolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)
Interacting Genes		27 interacting genes: APOD ASGR1 ATP6V0C BMP10 C14orf180 CCL4L2 CLEC7A CLRN2 CNIH3 DOLK MS4A13 PLPP6 PLPPR2 PLSCR1 SLC35B1 SLC35B4 SMAD3 SMCO4 TMEM100 TMEM14C TMEM218 TMEM229B TMEM97 TNF TSPAN2 TSPO2 VAMP3	32 interacting genes: AQP6 CD79A CISD2 CLDN5 CPLX4 CREB3L1 EBAG9 ERGIC3 ERP29 FAM209A FAM210B FFAR2 GPR152 GPX8 HSD17B13 KASH5 LHFPL5 LMNA MMGT1 MUC1 PDZK1IP1 PVR RHBDL2 SCARA5 SLC18A1 STOM TBXA2R TMEM130 TMEM237 TMEM52B TYROBP VSIR
Entrez ID		64115	84912
HPRD ID		15160	11578
Ensembl ID		ENSG00000107738	ENSG00000205060
Uniprot IDs		Q9H7M9	Q969S0
PDB IDs		6MVL 6OIL 6U6V
Enriched GO Terms of Interacting Partners?
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