APLP2 and SLC13A1

Number of citations of the paper that reports this interaction (PubMedID 18407958)
29

Data Source:
BioGRID (protein complementation assay)

		APLP2	SLC13A1
Description		amyloid beta precursor like protein 2	solute carrier family 13 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding	Sodium:sulfate Symporter Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)
Interacting Genes		24 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 KCNJ1 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 VKORC1 ZNF512B	31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 SLC9A3R1 SLC9A3R2 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3
Entrez ID		334	6561
HPRD ID		00103	08394
Ensembl ID		ENSG00000084234	ENSG00000081800
Uniprot IDs		A0A140VJE9 B4E3I5 Q06481	A4D0X1 Q2NKK0 Q9BZW2
PDB IDs		5JBT 5TPT
Enriched GO Terms of Interacting Partners?
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