APLP2 and KCNJ1

		APLP2	KCNJ1
Description		amyloid beta precursor like protein 2	potassium inwardly rectifying channel subfamily J member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane Extracellular Exosome	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding	Inward Rectifier Potassium Channel Activity ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity	Potassium Ion Transport Excretion Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Potassium transport channels
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Bethanidine Glimepiride Minoxidil Acetohexamide Tolbutamide Glymidine Yohimbine Agmatine Butamben
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		24 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 KCNJ1 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 VKORC1 ZNF512B	10 interacting genes: APLP2 CTSV EI24 GOLGA3 NID2 PRKCD SGK1 SH3RF1 SLC9A3R1 SLC9A3R2
Entrez ID		334	3758
HPRD ID		00103	08981
Ensembl ID		ENSG00000084234	ENSG00000151704
Uniprot IDs		A0A140VJE9 B4E3I5 Q06481	A0A024R3K6 A8K432 P48048
PDB IDs		5JBT 5TPT
Enriched GO Terms of Interacting Partners?
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