APLP2 and JUNB

Number of citations of the paper that reports this interaction (PubMedID 20195357)
31

Data Source:
BioGRID (pull down)

		APLP2	JUNB
Description		amyloid beta precursor like protein 2	JunB proto-oncogene, AP-1 transcription factor subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane Extracellular Exosome	Chromatin Nucleoplasm Transcription Regulator Complex Transcription Factor AP-1 Complex
	Molecular Function	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Osteoclast Differentiation Osteoblast Proliferation Regulation Of Cell Population Proliferation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription NGF-stimulated transcription Nuclear events stimulated by ALK signaling in cancer
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		24 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 KCNJ1 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 VKORC1 ZNF512B	39 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG UBA6 UBE2I USP24 ZNF595 ZSWIM9
Entrez ID		334	3726
HPRD ID		00103	01303
Ensembl ID		ENSG00000084234	ENSG00000171223
Uniprot IDs		A0A140VJE9 B4E3I5 Q06481	P17275 Q5U079
PDB IDs		5JBT 5TPT
Enriched GO Terms of Interacting Partners?
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