APLP2 and APBB3

Number of citations of the paper that reports this interaction (PubMedID 10081969)
9

Data Source:
HPRD (in vitro)

		APLP2	APBB3
Description		amyloid beta precursor like protein 2	amyloid beta precursor protein binding family B member 3
Image
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol Actin Cytoskeleton Membrane
	Molecular Function	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding	Amyloid-beta Binding Protein Binding Transcription Factor Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity	Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Secretion
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576)	Serum immune biomarker levels ( 32066700)
Interacting Genes		24 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 KCNJ1 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 VKORC1 ZNF512B	6 interacting genes: APLP2 APP EGFR ERBB2 PDPK1 RAB4A
Entrez ID		334	10307
HPRD ID		00103	04089
Ensembl ID		ENSG00000084234	ENSG00000113108
Uniprot IDs		A0A140VJE9 B4E3I5 Q06481	O95704 Q59EH2 Q96DX9
PDB IDs		5JBT 5TPT	2DYQ 2YSC
Enriched GO Terms of Interacting Partners?
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