MDFIC and SOCS4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		MDFIC	SOCS4
Description		MyoD family inhibitor domain containing	suppressor of cytokine signaling 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Phosphatidylinositol 3-kinase Complex
	Molecular Function	Protein Binding Transcription Factor Binding Cyclin Binding Tat Protein Binding DNA-binding Transcription Factor Binding	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of JNK Cascade Positive Regulation Of Viral Transcription	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphate Biosynthetic Process
Pathways			RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Body mass index ( 26426971 28892062) Clozapine-induced cytotoxicity ( 25656473) Drug experimentation measurement ( 30718321) General risk tolerance (MTAG) ( 30643258) Hip circumference ( 28552196) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Number of sexual partners ( 30643258) Obesity ( 23818313) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Smoking status (ever vs never smokers) ( 30643258) Tonsillectomy ( 27182965 28928442)	Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817)
Interacting Genes		4 interacting genes: CCNT1 CDK9 RPS6KA5 SOCS4	11 interacting genes: CNMD EGFR LDHAL6B MDFIC NR4A1 PALS1 PLPP6 SPRY1 TEKT4 TNK2 VWF
Entrez ID		29969	122809
HPRD ID		17103	18084
Ensembl ID		ENSG00000135272	ENSG00000180008
Uniprot IDs		Q9P1T7	Q5H9R6 Q8WXH5
PDB IDs			2IZV
Enriched GO Terms of Interacting Partners?
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