SOCS4 and PLPP6

Number of citations of the paper that reports this interaction (PubMedID 25814554)
26

Data Source:
BioGRID (two hybrid)

		SOCS4	PLPP6
Description		suppressor of cytokine signaling 4	phospholipid phosphatase 6
Image			No pdb structure
GO Annotations	Cellular Component	Phosphatidylinositol 3-kinase Complex	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphate Biosynthetic Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation
Pathways		RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cholesterol biosynthesis
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817)
Interacting Genes		11 interacting genes: CNMD EGFR LDHAL6B MDFIC NR4A1 PALS1 PLPP6 SPRY1 TEKT4 TNK2 VWF	57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR
Entrez ID		122809	403313
HPRD ID		18084	17397
Ensembl ID		ENSG00000180008	ENSG00000205808
Uniprot IDs		Q5H9R6 Q8WXH5	Q8IY26
PDB IDs		2IZV
Enriched GO Terms of Interacting Partners?
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