SOCS4 and TEKT4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SOCS4	TEKT4
Description		suppressor of cytokine signaling 4	tektin 4
Image			No pdb structure
GO Annotations	Cellular Component	Phosphatidylinositol 3-kinase Complex	Nucleus Microtubule Cytoskeleton Sperm Flagellum
	Molecular Function	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphate Biosynthetic Process	Cilium Assembly Cilium Movement Involved In Cell Motility
Pathways		RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817)
Interacting Genes		11 interacting genes: CNMD EGFR LDHAL6B MDFIC NR4A1 PALS1 PLPP6 SPRY1 TEKT4 TNK2 VWF	104 interacting genes: ACBD4 AKAP8L ALAS1 AMMECR1 ANKRD55 ARID5A ATG5 BCL6 BLZF1 BORCS8-MEF2B C11orf1 C1orf109 C9orf24 CTDSP1 DDIT4L EFHC2 EYA2 FAM220A GATA1 GPSM1 GRB10 GSE1 HCK HNRNPH1 HNRNPM HOXA1 HOXB5 HOXC8 IKZF3 INCA1 KPRP KRT15 KRT18 KRT34 KRT35 KRT75 KRT86 KRTAP11-1 KRTAP13-1 KRTAP13-3 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP26-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LASP1 LMCD1 LNX1 MAGEA4 MIIP MORN3 MYOZ3 NANOS3 NFKBID NR5A1 PCSK5 PHF11 PKP2 PLAGL2 POLDIP3 PPP1R13B PPP1R32 PRDM14 PRDM6 PROP1 PSMA1 PTH1R RAMAC RARA RBM48 RECK RFX6 RUSC1 SCN5A SLC25A6 SMAD3 SOCS4 SPATA8 SPATC1L SPG21 SUV39H1 TADA2A TEKT1 TFAP4 TOX2 TRIB3 TRIP6 TSPAN4 UBASH3A USP2 VGLL1 ZFP90 ZIM2 ZMYND12 ZNF20 ZNF417 ZNF426 ZNF474 ZNF552 ZNF581 ZNF655 ZNF688
Entrez ID		122809	150483
HPRD ID		18084	14518
Ensembl ID		ENSG00000180008	ENSG00000163060
Uniprot IDs		Q5H9R6 Q8WXH5	A0A384MEB7 Q8WW24
PDB IDs		2IZV
Enriched GO Terms of Interacting Partners?
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