SOCS4 and MDFIC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SOCS4	MDFIC
Description		suppressor of cytokine signaling 4	MyoD family inhibitor domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Phosphatidylinositol 3-kinase Complex	Nucleus Nucleolus Cytoplasm
	Molecular Function	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding Transcription Factor Binding Cyclin Binding Tat Protein Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphate Biosynthetic Process	Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of JNK Cascade Positive Regulation Of Viral Transcription
Pathways		RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817)	Adventurousness ( 30643258) Body mass index ( 26426971 28892062) Clozapine-induced cytotoxicity ( 25656473) Drug experimentation measurement ( 30718321) General risk tolerance (MTAG) ( 30643258) Hip circumference ( 28552196) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Number of sexual partners ( 30643258) Obesity ( 23818313) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Smoking status (ever vs never smokers) ( 30643258) Tonsillectomy ( 27182965 28928442)
Interacting Genes		11 interacting genes: CNMD EGFR LDHAL6B MDFIC NR4A1 PALS1 PLPP6 SPRY1 TEKT4 TNK2 VWF	4 interacting genes: CCNT1 CDK9 RPS6KA5 SOCS4
Entrez ID		122809	29969
HPRD ID		18084	17103
Ensembl ID		ENSG00000180008	ENSG00000135272
Uniprot IDs		Q5H9R6 Q8WXH5	Q9P1T7
PDB IDs		2IZV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?