CDC5L and ZNF35

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		CDC5L	ZNF35
Gene Name		cell division cycle 5-like	zinc finger protein 35
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Nucleolus Cytoplasm Membrane Nuclear Speck Catalytic Step 2 Spliceosome	Cell Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Poly(A) RNA Binding WD40-repeat Domain Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Splicing Gene Expression Signal Transduction Involved In DNA Damage Checkpoint	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis Cellular Response To Retinoic Acid
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Osteoarthritis ( 22763110) Stroke (ischemic) ( 22941190)
Protein-Protein Interactions		69 interactors: AKAP6 AKAP9 BCAS2 CALM1 CCDC136 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GLTSCR1L GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HOOK1 KALRN KANSL1 KDM1A KIF3C KIF5B KRT18 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MYT1L ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF19 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 TRAF3IP1 TRAK1 TRIO TTF2 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZSCAN1	3 interactors: APP CDC5L CREB1
Entrez ID		988	7584
HPRD ID		04184	01920
Ensembl ID		ENSG00000096401	ENSG00000169981
Uniprot IDs		Q99459	B4DUB8 P13682
PDB IDs		2DIM 2DIN
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Mitotic Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process DNA Replication DNA-dependent DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Replication Initiation Organelle Organization Cellular Process DNA Recombinase Assembly Apoptotic Signaling Pathway DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Potassium Ion Transport Cellular Localization Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Cell Cycle Intracellular Signal Transduction Nitrogen Compound Metabolic Process Positive Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Establishment Of Localization In Cell Intrinsic Apoptotic Signaling Pathway Nucleotide-excision Repair, DNA Gap Filling Positive Regulation Of Potassium Ion Transmembrane Transport G2/M Transition Of Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Removal Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Telomere Maintenance Via Semi-conservative Replication Regulation Of Potassium Ion Transport Cellular Response To Heat Regulation Of Membrane Repolarization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Cell Cycle Phase Transition RNA Splicing Telomere Maintenance Via Recombination Nuclear DNA Replication Golgi To Plasma Membrane Protein Transport	Regulation Of Multicellular Organism Growth Notch Signaling Pathway Synaptic Growth At Neuromuscular Junction Regulation Of Cell Cycle Phase Transition Collateral Sprouting In Absence Of Injury Learning Or Memory Regulation Of Developmental Growth Cognition Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Axon Guidance MRNA Processing Forebrain Development Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Transcription By Competitive Promoter Binding Neuron Remodeling Regulation Of Cell Cycle Process Axonogenesis MRNA Metabolic Process Lung Saccule Development Axon Development RNA Processing Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Behavior Chemotaxis Cellular Response To Zinc Ion Type I Pneumocyte Differentiation Regulation Of Growth Secretion Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis RNA Metabolic Process Cell Morphogenesis Involved In Differentiation Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Osteoclast Differentiation Brain Development Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Stress Gene Expression Head Development Innate Immune Response Neuron Projection Development Cell Projection Morphogenesis Neuron Maturation MRNA Polyadenylation
Tagcloud ?		adjuvant adolescents analyse barcodes cdk4 determining digital encoded helicase histopathologic inactivator malignancy mdm2 nanostring neo networks operative osteosarcoma osteosarcomas paediatric panel quantify rb1 recql4 responded runx2 sporadic tp53 unfavourable
Tagcloud (Difference) ?		adjuvant adolescents analyse barcodes cdk4 determining digital encoded helicase histopathologic inactivator malignancy mdm2 nanostring neo networks operative osteosarcoma osteosarcomas paediatric panel quantify rb1 recql4 responded runx2 sporadic tp53 unfavourable
Tagcloud (Intersection) ?