UTRN and MARK2

Number of citations of the paper that reports this interaction (PMID 19945424)
7

Data Source:
BioGRID (pull down, enzymatic study)

		UTRN	MARK2
Gene Name		utrophin	MAP/microtubule affinity-regulating kinase 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Filopodium Membrane Neuromuscular Junction Protein Complex Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Nucleus Mitochondrion Actin Filament Plasma Membrane Membrane Lateral Plasma Membrane Basal Cortex Microtubule Bundle
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Lipid Binding Protein Kinase Activator Activity Poly(A) RNA Binding Tau-protein Kinase Activity
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Regulation Of Sodium Ion Transmembrane Transporter Activity	Mitochondrion Degradation Neuron Migration Protein Phosphorylation Positive Regulation Of Neuron Projection Development Wnt Signaling Pathway Peptidyl-threonine Phosphorylation Establishment Of Cell Polarity Activation Of Protein Kinase Activity Intracellular Signal Transduction Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Autophosphorylation Regulation Of Axonogenesis Regulation Of Cytoskeleton Organization Mitochondrion Localization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ACTA1 ACTN2 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCH5 MARK2 PGM5 PTPN12 SNTA1 SNTB1 SNTB2 UBC	23 interactors: BAIAP2 CAMK1 DVL3 GAB1 GSK3B HDAC7 KIF13B MAP3K3 MAPT MTCL1 NEDD4 NEDD4L PARD6A PINK1 PKD1 PRKCE RAB11FIP2 RNF41 STK11 UTRN YWHAB YWHAQ YWHAZ
Entrez ID		7402	2011
HPRD ID		00547	02753
Ensembl ID		ENSG00000152818	ENSG00000072518
Uniprot IDs		P46939 Q6LBS5	A8K2S4 Q7KZI7
PDB IDs		1BHD 1QAG	3IEC
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Actin-myosin Filament Sliding Muscle Filament Sliding Negative Regulation Of Peptidyl-cysteine S-nitrosylation Actin-mediated Cell Contraction Actin Filament-based Movement Movement Of Cell Or Subcellular Component Myotube Cell Development Regulation Of Sodium Ion Transmembrane Transport Cellular Localization Cardiac Muscle Cell Action Potential Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Membrane Potential Myotube Differentiation Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Calcium-dependent Cell-matrix Adhesion Nerve Development Regulation Of Neuron Projection Development Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Glial Cell Development Positive Regulation Of Neurogenesis Peripheral Nervous System Development Regulation Of Ion Transmembrane Transport Regulation Of Cell Projection Organization Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cell Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development Microspike Assembly Regulation Of Neuron Differentiation Positive Regulation Of Cellular Protein Catabolic Process	Regulation Of Cellular Component Organization Regulation Of Cellular Localization Regulation Of Intracellular Transport Signaling Positive Regulation Of Signal Transduction Cell Communication Positive Regulation Of Transport Signal Transduction Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrion Organization Positive Regulation Of Organelle Organization Positive Regulation Of Phosphorylation Positive Regulation Of Protein Metabolic Process Cellular Response To Stimulus Positive Regulation Of Protein Kinase Activity Regulation Of Signaling Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Regulation Of Kinase Activity Regulation Of Protein Localization Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Transferase Activity Cellular Response To Organic Substance Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Neuron Projection Development Negative Regulation Of Transport Regulation Of MAPK Cascade Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Protein Modification Process Negative Regulation Of Sodium Ion Transport Regulation Of Establishment Of Protein Localization Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Programmed Cell Death Regulation Of Cell Projection Organization Cell Death Death Response To Stimulus Positive Regulation Of Metabolic Process Intracellular Signal Transduction Regulation Of Sodium Ion Transport
Tagcloud ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs	adjusting aor assisted backgroundlimited children china conclusionsscreen habits height hrs inverted lifestyle mark0 methodsa modes multilevel obese obesity overweight question questions results15 school schools screen spent travel
Tagcloud (Difference) ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs	adjusting aor assisted backgroundlimited children china conclusionsscreen habits height hrs inverted lifestyle mark0 methodsa modes multilevel obese obesity overweight question questions results15 school schools screen spent travel
Tagcloud (Intersection) ?