UTRN and MARCH5

Number of citations of the paper that reports this interaction (PMID 16936636)
90

Data Source:
HPRD (in vivo, in vitro)

		UTRN	MARCH5
Gene Name		utrophin	membrane-associated ring finger (C3HC4) 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Filopodium Membrane Neuromuscular Junction Protein Complex Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity GTPase Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Regulation Of Sodium Ion Transmembrane Transporter Activity	Protein Polyubiquitination Protein Autoubiquitination Protein Localization To Mitochondrion Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cell Aging
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ACTA1 ACTN2 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCH5 MARK2 PGM5 PTPN12 SNTA1 SNTB1 SNTB2 UBC	17 interactors: AKTIP FATE1 FIS1 MAP1B MFN2 SOD1 TANK UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2I UBE2N UBE2T UBE2W UTRN
Entrez ID		7402	54708
HPRD ID		00547	07909
Ensembl ID		ENSG00000152818	ENSG00000198060
Uniprot IDs		P46939 Q6LBS5	B4DGV8 Q9NX47
PDB IDs		1BHD 1QAG
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Actin-myosin Filament Sliding Muscle Filament Sliding Negative Regulation Of Peptidyl-cysteine S-nitrosylation Actin-mediated Cell Contraction Actin Filament-based Movement Movement Of Cell Or Subcellular Component Myotube Cell Development Regulation Of Sodium Ion Transmembrane Transport Cellular Localization Cardiac Muscle Cell Action Potential Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Membrane Potential Myotube Differentiation Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Calcium-dependent Cell-matrix Adhesion Nerve Development Regulation Of Neuron Projection Development Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Glial Cell Development Positive Regulation Of Neurogenesis Peripheral Nervous System Development Regulation Of Ion Transmembrane Transport Regulation Of Cell Projection Organization Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cell Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development Microspike Assembly Regulation Of Neuron Differentiation Positive Regulation Of Cellular Protein Catabolic Process	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Protein Monoubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Protein Modification Process Immune Response-regulating Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Transferase Activity Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Stress Proteolysis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Immune Response Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Mitochondrial Fusion Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Cellular Protein Metabolic Process Response To Stress Regulation Of Immune System Process Innate Immune Response Regulation Of Immune Response
Tagcloud ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs
Tagcloud (Difference) ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs
Tagcloud (Intersection) ?