MARK2 and KIF13B

Number of citations of the paper that reports this interaction (PMID 20194617)
7

Data Source:
BioGRID (pull down, enzymatic study)

		MARK2	KIF13B
Gene Name		MAP/microtubule affinity-regulating kinase 2	kinesin family member 13B
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Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Actin Filament Plasma Membrane Membrane Lateral Plasma Membrane Basal Cortex Microtubule Bundle	Cytoplasm Kinesin Complex Microtubule Axon
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Lipid Binding Protein Kinase Activator Activity Poly(A) RNA Binding Tau-protein Kinase Activity	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Protein Kinase Binding 14-3-3 Protein Binding
	Biological Process	Mitochondrion Degradation Neuron Migration Protein Phosphorylation Positive Regulation Of Neuron Projection Development Wnt Signaling Pathway Peptidyl-threonine Phosphorylation Establishment Of Cell Polarity Activation Of Protein Kinase Activity Intracellular Signal Transduction Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Autophosphorylation Regulation Of Axonogenesis Regulation Of Cytoskeleton Organization Mitochondrion Localization	Protein Targeting Microtubule-based Movement Signal Transduction Metabolic Process T Cell Activation Regulation Of Axonogenesis
Pathways
Drugs
Diseases
GWAS			Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Response to statin therapy ( 20339536)
Protein-Protein Interactions		23 interactors: BAIAP2 CAMK1 DVL3 GAB1 GSK3B HDAC7 KIF13B MAP3K3 MAPT MTCL1 NEDD4 NEDD4L PARD6A PINK1 PKD1 PRKCE RAB11FIP2 RNF41 STK11 UTRN YWHAB YWHAQ YWHAZ	3 interactors: DLG1 DLG4 MARK2
Entrez ID		2011	23303
HPRD ID		02753	09556
Ensembl ID		ENSG00000072518	ENSG00000197892
Uniprot IDs		A8K2S4 Q7KZI7	Q9NQT8
PDB IDs		3IEC	2COW 3FM8 3GBJ 3MDB
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Regulation Of Cellular Localization Regulation Of Intracellular Transport Signaling Positive Regulation Of Signal Transduction Cell Communication Positive Regulation Of Transport Signal Transduction Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrion Organization Positive Regulation Of Organelle Organization Positive Regulation Of Phosphorylation Positive Regulation Of Protein Metabolic Process Cellular Response To Stimulus Positive Regulation Of Protein Kinase Activity Regulation Of Signaling Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Regulation Of Kinase Activity Regulation Of Protein Localization Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Transferase Activity Cellular Response To Organic Substance Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Neuron Projection Development Negative Regulation Of Transport Regulation Of MAPK Cascade Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Protein Modification Process Negative Regulation Of Sodium Ion Transport Regulation Of Establishment Of Protein Localization Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Programmed Cell Death Regulation Of Cell Projection Organization Cell Death Death Response To Stimulus Positive Regulation Of Metabolic Process Intracellular Signal Transduction Regulation Of Sodium Ion Transport	Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Establishment Or Maintenance Of Cell Polarity Protein Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Receptor Clustering Nucleotide Phosphorylation Locomotion Movement Of Cell Or Subcellular Component Positive Regulation Of Catalytic Activity Generation Of Neurons Neurogenesis Regulation Of Membrane Potential Activation Of Protein Kinase Activity Phosphorylation Regulation Of Cellular Component Organization T Cell Cytokine Production Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Protein Localization To Membrane Maintenance Of Apical/basal Cell Polarity Axon Guidance Organelle Localization Regulation Of Ion Transmembrane Transport Nervous System Development Negative Regulation Of Receptor Internalization Regulation Of Catalytic Activity Cellular Localization Positive Regulation Of Protein Kinase Activity Peristalsis Cytokine Production Involved In Immune Response Immunological Synapse Formation Locomotory Exploration Behavior Positive Regulation Of Kinase Activity Regulation Of Cytoskeleton Organization Dendritic Spine Morphogenesis Synaptic Vesicle Maturation Maintenance Of Cell Polarity Axonogenesis Positive Regulation Of Transferase Activity Nucleotide Metabolic Process Axon Development Vocalization Behavior Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Phosphate-containing Compound Metabolic Process Amyloid Precursor Protein Metabolic Process
Tagcloud ?		adjusting aor assisted backgroundlimited children china conclusionsscreen habits height hrs inverted lifestyle mark0 methodsa modes multilevel obese obesity overweight question questions results15 school schools screen spent travel
Tagcloud (Difference) ?		adjusting aor assisted backgroundlimited children china conclusionsscreen habits height hrs inverted lifestyle mark0 methodsa modes multilevel obese obesity overweight question questions results15 school schools screen spent travel
Tagcloud (Intersection) ?