UTRN and DMD

Number of citations of the paper that reports this interaction (PMID 10767429)
2

Data Source:
HPRD (in vitro)

		UTRN	DMD
Gene Name		utrophin	dystrophin
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Filopodium Membrane Neuromuscular Junction Protein Complex Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Nucleus Cytosol Cytoskeleton Plasma Membrane Cell Surface Actin Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Filopodium Filopodium Membrane Sarcolemma Costamere Protein Complex Membrane Raft Postsynaptic Membrane
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Regulation Of Sodium Ion Transmembrane Transporter Activity	Regulation Of Heart Rate Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Extracellular Matrix Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Peptide Biosynthetic Process Cellular Protein Complex Assembly Motile Cilium Assembly Positive Regulation Of Neuron Differentiation Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Striated Muscle Contraction Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS			Response to antidepressant treatment ( 22041458)
Protein-Protein Interactions		16 interactors: ACTA1 ACTN2 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCH5 MARK2 PGM5 PTPN12 SNTA1 SNTB1 SNTB2 UBC	27 interactors: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN
Entrez ID		7402	1756
HPRD ID		00547	02303
Ensembl ID		ENSG00000152818	ENSG00000198947
Uniprot IDs		P46939 Q6LBS5	A1L0U9 A7E212 P11532 Q16484 Q4G0X0
PDB IDs		1BHD 1QAG	1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Actin-myosin Filament Sliding Muscle Filament Sliding Negative Regulation Of Peptidyl-cysteine S-nitrosylation Actin-mediated Cell Contraction Actin Filament-based Movement Movement Of Cell Or Subcellular Component Myotube Cell Development Regulation Of Sodium Ion Transmembrane Transport Cellular Localization Cardiac Muscle Cell Action Potential Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Membrane Potential Myotube Differentiation Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Calcium-dependent Cell-matrix Adhesion Nerve Development Regulation Of Neuron Projection Development Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Glial Cell Development Positive Regulation Of Neurogenesis Peripheral Nervous System Development Regulation Of Ion Transmembrane Transport Regulation Of Cell Projection Organization Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cell Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development Microspike Assembly Regulation Of Neuron Differentiation Positive Regulation Of Cellular Protein Catabolic Process	Muscle Contraction Muscle System Process Muscle Cell Development Myofibril Assembly Actomyosin Structure Organization Organelle Assembly Cellular Component Assembly Muscle Structure Development Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Synaptic Vesicle Priming Striated Muscle Cell Differentiation Organ Development Cytoskeleton Organization Organelle Organization Muscle Organ Development Positive Regulation Of Proteolysis Cell Development System Development Positive Regulation Of Peptidase Activity Cell Differentiation Involved In Embryonic Placenta Development Actin-myosin Filament Sliding Muscle Filament Sliding Movement Of Cell Or Subcellular Component Regulation Of Sodium Ion Transmembrane Transport Microtubule-based Process Actin-mediated Cell Contraction Programmed Necrotic Cell Death Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Necrotic Cell Death Multicellular Organismal Development Sarcomere Organization Neuromuscular Junction Development Synaptic Vesicle Exocytosis Anatomical Structure Development Actin Filament-based Movement Cell-cell Signaling Heart Contraction Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Calcium-dependent Cell-matrix Adhesion Regulation Of Sodium Ion Transport Anatomical Structure Morphogenesis Viral Process Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death
Tagcloud ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs	2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Difference) ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs	2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Intersection) ?