UTRN and DTNB

Number of citations of the paper that reports this interaction (PMID 10545507)
24

Data Source:
HPRD (in vitro)

		UTRN	DTNB
Gene Name		utrophin	dystrobrevin, beta
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Filopodium Membrane Neuromuscular Junction Protein Complex Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Cytoplasm Synapse
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding	Zinc Ion Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS			Coronary heart disease ( 21347282) Height ( 18391951) Multiple myeloma ( 22120009)
Protein-Protein Interactions		16 interactors: ACTA1 ACTN2 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCH5 MARK2 PGM5 PTPN12 SNTA1 SNTB1 SNTB2 UBC	30 interactors: ABI2 ABI3 BEGAIN CCDC85B CEP55 CEP63 DMD DTNBP1 GGA1 HMG20A KIF5A KIF5B KRT31 KRT40 MTUS2 NDEL1 NUP62 PPFIA1 PPFIBP2 PRTFDC1 SNTG1 SNTG2 SPZ1 TRAF2 TSACC TXLNA USHBP1 UTRN VCP ZBTB9
Entrez ID		7402	1838
HPRD ID		00547	09091
Ensembl ID		ENSG00000152818	ENSG00000138101
Uniprot IDs		P46939 Q6LBS5	B7Z6A9 E9PEY4 O60941 Q1I0L3
PDB IDs		1BHD 1QAG
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Actin-myosin Filament Sliding Muscle Filament Sliding Negative Regulation Of Peptidyl-cysteine S-nitrosylation Actin-mediated Cell Contraction Actin Filament-based Movement Movement Of Cell Or Subcellular Component Myotube Cell Development Regulation Of Sodium Ion Transmembrane Transport Cellular Localization Cardiac Muscle Cell Action Potential Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Membrane Potential Myotube Differentiation Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Calcium-dependent Cell-matrix Adhesion Nerve Development Regulation Of Neuron Projection Development Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Glial Cell Development Positive Regulation Of Neurogenesis Peripheral Nervous System Development Regulation Of Ion Transmembrane Transport Regulation Of Cell Projection Organization Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cell Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development Microspike Assembly Regulation Of Neuron Differentiation Positive Regulation Of Cellular Protein Catabolic Process	Cytoskeleton-dependent Intracellular Transport Cellular Localization Establishment Of Localization In Cell Microtubule-based Movement Microtubule-based Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Vesicle Transport Along Microtubule Movement Of Cell Or Subcellular Component Intracellular Transport Regulation Of Sodium Ion Transmembrane Transport Generation Of Neurons Nuclear Envelope Disassembly Organelle Localization Cell Projection Organization Microtubule-based Process Regulation Of Establishment Of Protein Localization To Plasma Membrane Neurogenesis Establishment Of Vesicle Localization Axon Cargo Transport Neuron Projection Development Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Centrosome Cycle Vesicle Localization Nervous System Development Cell Projection Morphogenesis Organelle Transport Along Microtubule Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cell-matrix Adhesion Cell Part Morphogenesis Nuclear Envelope Organization Regulation Of Sodium Ion Transport Stress Granule Disassembly Establishment Of Glial Blood-brain Barrier Regulation Of Cellular Component Organization Neuron Development Synaptic Transmission Protein Complex Assembly Regulation Of Cellular Localization Regulation Of Ion Transport Negative Regulation Of Peptidyl-cysteine S-nitrosylation Developmental Process Cell Morphogenesis Neuron Projection Morphogenesis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Centrosome Organization Establishment Of Organelle Localization Activation Of Cysteine-type Endopeptidase Activity Mitotic Cell Cycle Process Neuron Differentiation
Tagcloud ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs	attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol
Tagcloud (Difference) ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs	attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol
Tagcloud (Intersection) ?