DMD and KRT19

Number of citations of the paper that reports this interaction (PMID 16000376)
15

Data Source:
HPRD (in vitro, in vivo)

		DMD	KRT19
Gene Name		dystrophin	keratin 19, type I
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Plasma Membrane Cell Surface Actin Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Filopodium Filopodium Membrane Sarcolemma Costamere Protein Complex Membrane Raft Postsynaptic Membrane	Intermediate Filament Dystrophin-associated Glycoprotein Complex Z Disc Sarcolemma Costamere Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein Complex Binding
	Biological Process	Regulation Of Heart Rate Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Extracellular Matrix Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Peptide Biosynthetic Process Cellular Protein Complex Assembly Motile Cilium Assembly Positive Regulation Of Neuron Differentiation Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Viral Process Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development
Pathways		Striated Muscle Contraction Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS		Response to antidepressant treatment ( 22041458)
Protein-Protein Interactions		27 interactors: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN	37 interactors: ABI2 AMOTL2 APC C10orf10 C1orf109 CARD9 CCDC146 CEP57L1 DGCR6L DMD EIF4E2 EIF4ENIF1 EXOC8 FAM107A FAM124B FANCG HAUS1 HGS IKZF3 KDM1A KIFC3 KRT15 KRT2 KRT6B PCM1 PLEKHA5 PNN POLR1C PPP1R18 SFI1 TBC1D7 TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		1756	3880
HPRD ID		02303	01007
Ensembl ID		ENSG00000198947	ENSG00000171345
Uniprot IDs		A1L0U9 A7E212 P11532 Q16484 Q4G0X0	P08727
PDB IDs		1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Muscle Cell Development Myofibril Assembly Actomyosin Structure Organization Organelle Assembly Cellular Component Assembly Muscle Structure Development Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Synaptic Vesicle Priming Striated Muscle Cell Differentiation Organ Development Cytoskeleton Organization Organelle Organization Muscle Organ Development Positive Regulation Of Proteolysis Cell Development System Development Positive Regulation Of Peptidase Activity Cell Differentiation Involved In Embryonic Placenta Development Actin-myosin Filament Sliding Muscle Filament Sliding Movement Of Cell Or Subcellular Component Regulation Of Sodium Ion Transmembrane Transport Microtubule-based Process Actin-mediated Cell Contraction Programmed Necrotic Cell Death Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Necrotic Cell Death Multicellular Organismal Development Sarcomere Organization Neuromuscular Junction Development Synaptic Vesicle Exocytosis Anatomical Structure Development Actin Filament-based Movement Cell-cell Signaling Heart Contraction Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Calcium-dependent Cell-matrix Adhesion Regulation Of Sodium Ion Transport Anatomical Structure Morphogenesis Viral Process Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death	Cytoplasmic Microtubule Organization Organelle Organization Mitotic Cell Cycle Process Microtubule Cytoskeleton Organization Cell Cycle Process Mitotic Cell Cycle Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Muscle Cell Cellular Homeostasis Cell Cycle Keratinocyte Activation Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of SUMO Transferase Activity Exocyst Assembly Microtubule Anchoring Nucleus Localization Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization
Tagcloud ?		2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2	allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately
Tagcloud (Difference) ?		2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2	allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately
Tagcloud (Intersection) ?