DMD and SNTB1

Number of citations of the paper that reports this interaction (PMID 7844150)
40

Data Source:
HPRD (in vitro, in vivo)

		DMD	SNTB1
Gene Name		dystrophin	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Plasma Membrane Cell Surface Actin Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Filopodium Filopodium Membrane Sarcolemma Costamere Protein Complex Membrane Raft Postsynaptic Membrane	Cytoplasm Cytoskeleton Focal Adhesion Dystrophin-associated Glycoprotein Complex Sarcolemma Protein Complex Synapse
	Molecular Function	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding	Actin Binding Protein Binding Calmodulin Binding PDZ Domain Binding
	Biological Process	Regulation Of Heart Rate Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Extracellular Matrix Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Peptide Biosynthetic Process Cellular Protein Complex Assembly Motile Cilium Assembly Positive Regulation Of Neuron Differentiation Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Muscle Contraction
Pathways		Striated Muscle Contraction Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS		Response to antidepressant treatment ( 22041458)	Myopia (pathological) ( 23406873)
Protein-Protein Interactions		27 interactors: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN	11 interactors: ABCA1 ADRA1D BAI1 DGKZ DMD DTNA KCNJ12 MAPK12 SCN4A SCN5A UTRN
Entrez ID		1756	6641
HPRD ID		02303	02490
Ensembl ID		ENSG00000198947	ENSG00000172164
Uniprot IDs		A1L0U9 A7E212 P11532 Q16484 Q4G0X0	Q13884
PDB IDs		1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Muscle Cell Development Myofibril Assembly Actomyosin Structure Organization Organelle Assembly Cellular Component Assembly Muscle Structure Development Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Synaptic Vesicle Priming Striated Muscle Cell Differentiation Organ Development Cytoskeleton Organization Organelle Organization Muscle Organ Development Positive Regulation Of Proteolysis Cell Development System Development Positive Regulation Of Peptidase Activity Cell Differentiation Involved In Embryonic Placenta Development Actin-myosin Filament Sliding Muscle Filament Sliding Movement Of Cell Or Subcellular Component Regulation Of Sodium Ion Transmembrane Transport Microtubule-based Process Actin-mediated Cell Contraction Programmed Necrotic Cell Death Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Necrotic Cell Death Multicellular Organismal Development Sarcomere Organization Neuromuscular Junction Development Synaptic Vesicle Exocytosis Anatomical Structure Development Actin Filament-based Movement Cell-cell Signaling Heart Contraction Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Calcium-dependent Cell-matrix Adhesion Regulation Of Sodium Ion Transport Anatomical Structure Morphogenesis Viral Process Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death	Muscle Contraction Muscle System Process Regulation Of Sodium Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Regulation Of Heart Contraction Regulation Of Sodium Ion Transport Regulation Of Ion Transport Signaling Cell Communication Action Potential Striated Muscle Contraction Cell-cell Signaling Regulation Of Sodium Ion Transmembrane Transporter Activity Neuronal Action Potential Cardiac Muscle Cell Action Potential Membrane Depolarization During Action Potential Positive Regulation Of Sodium Ion Transport Regulation Of Membrane Potential Muscle Organ Development Cardiac Muscle Contraction Positive Regulation Of Cell-matrix Adhesion Transmission Of Nerve Impulse Blood Circulation Heart Contraction Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Cellular Process Regulation Of Striated Muscle Contraction Establishment Of Glial Blood-brain Barrier Peripheral Nervous System Development Membrane Depolarization Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion G-protein Coupled Receptor Signaling Pathway Muscle Structure Development Negative Regulation Of Peptidyl-cysteine S-nitrosylation Membrane Depolarization During SA Node Cell Action Potential Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Interleukin-1 Beta Secretion Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Synaptic Transmission Ion Transmembrane Transport Regulation Of Muscle Contraction SA Node Cell Action Potential Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier AV Node Cell To Bundle Of His Cell Communication Cellular Response To Stimulus
Tagcloud ?		2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Difference) ?		2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Intersection) ?