PDLIM5 and GFI1B

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDLIM5	GFI1B
Gene Name		PDZ and LIM domain 5	growth factor independent 1B transcription repressor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Postsynaptic Density Actin Cytoskeleton Membrane Z Disc Cell Junction Neuron Projection Postsynaptic Membrane	Nucleus Transcription Factor Complex Nuclear Matrix
	Molecular Function	Actin Binding Protein Kinase C Binding Zinc Ion Binding Actinin Binding Protein N-terminus Binding	RNA Polymerase II Transcription Factor Binding DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Synapse Assembly Regulation Of Dendritic Spine Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Proliferation Chromatin Modification Hemopoiesis Regulation Of Histone H3-K4 Methylation
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 19767753) Visceral fat ( 22589738)
Protein-Protein Interactions		13 interactors: ACTB ACTN1 CACNA1B CCDC136 COIL GFI1B KRT40 KRTAP10-7 PRKCB PRKCE PRKCG TRIM39 ZYX	71 interactors: ACTN1 AES AGPAT6 AGRN AJUBA ANKS3 ATXN2 BECN1 BEGAIN BEND5 BRCA1 BRE CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3
Entrez ID		10611	8328
HPRD ID		05799	05088
Ensembl ID		ENSG00000163110	ENSG00000165702
Uniprot IDs		B7Z481 B7Z8X5 Q96HC4	Q5VTD9
PDB IDs		2DAR 2UZC
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Pain Response To Morphine Immune Response-activating Cell Surface Receptor Signaling Pathway Activation Of Phospholipase C Activity Calcium Ion Transport Positive Regulation Of Phospholipase C Activity Cell-cell Signaling Actin Filament Bundle Assembly Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Phospholipase Activity Positive Regulation Of Cellular Glucuronidation Positive Regulation Of Mismatch Repair Regulation Of Phospholipase Activity Multicellular Organismal Response To Stress Adherens Junction Organization Positive Regulation Of Lipase Activity Response To Ammonium Ion Response To Stress Immune Response-regulating Signaling Pathway Immune System Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Adhesion Negative Regulation Of Protein Ubiquitination Regulation Of Mismatch Repair TRAM-dependent Toll-like Receptor 4 Signaling Pathway Histone H3-T6 Phosphorylation Negative Regulation Of Protein Catabolic Process Cellular Response To Growth Factor Stimulus Synaptic Transmission Behavior Response To Growth Factor Chromatin Modification Response To Alkaloid Positive Regulation Of Immune Response Protein Localization To Tight Junction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway	Regulation Of Cellular Process Cell Communication Regulation Of Cellular Component Organization Regulation Of Signaling Extracellular Matrix Organization Extracellular Structure Organization Signaling Cellular Response To Stimulus Signal Transduction Response To Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Regulation Of Growth Negative Regulation Of Wnt Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Canonical Wnt Signaling Pathway Developmental Process Secretion Negative Regulation Of Signaling Regulation Of Locomotion Cellular Process Regulation Of Cellular Component Movement Focal Adhesion Assembly Protein Localization Protein Ubiquitination Cellular Localization Negative Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Cell-substrate Adhesion Adherens Junction Assembly Cell Differentiation Cellular Component Assembly Neurogenesis Auditory Receptor Cell Fate Commitment Anatomical Structure Development Regulation Of Gene Expression Regulation Of Proteolysis Regulation Of Apoptotic Process Cell-substrate Junction Assembly Regulation Of I-kappaB Kinase/NF-kappaB Signaling Secretion By Cell Regulation Of Cell Proliferation Receptor Clustering Regulation Of Vesicle-mediated Transport
Tagcloud ?		14e4 1c4 3h1 4d2 bands bmpr1b copy e5 hybridisation losses ontology pde6d ptc ptcs ptma slitrk1 slitrk5 slitrk6 srm t1 taf12 tp73 transgenics trk trp73 tumourigenesis twist2 unc5c ythdf2	appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge
Tagcloud (Difference) ?		14e4 1c4 3h1 4d2 bands bmpr1b copy e5 hybridisation losses ontology pde6d ptc ptcs ptma slitrk1 slitrk5 slitrk6 srm t1 taf12 tp73 transgenics trk trp73 tumourigenesis twist2 unc5c ythdf2	appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge
Tagcloud (Intersection) ?