GFI1B and DNAJA3

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GFI1B	DNAJA3
Gene Name		growth factor independent 1B transcription repressor	DnaJ (Hsp40) homolog, subfamily A, member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nuclear Matrix	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Actin Filament IkappaB Kinase Complex Extrinsic Component Of Plasma Membrane Cell Junction Neuromuscular Junction I-kappaB/NF-kappaB Complex Mitochondrial Nucleoid Intracellular Membrane-bounded Organelle Postsynaptic Membrane
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Protein Binding Metal Ion Binding	Small GTPase Regulator Activity Interferon-gamma Receptor Binding Protein Binding ATP Binding Transcription Factor Binding Protein Kinase Binding Hsp70 Protein Binding Receptor Tyrosine Kinase Binding Metal Ion Binding NF-kappaB Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Proliferation Chromatin Modification Hemopoiesis Regulation Of Histone H3-K4 Methylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitochondrial DNA Replication Protein Folding Negative Regulation Of Protein Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Neuromuscular Junction Development Cell Aging Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity T Cell Differentiation In Thymus Response To Interferon-gamma Protein Refolding Positive Regulation Of T Cell Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Catalytic Activity Protein Stabilization Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		71 interactors: ACTN1 AES AGPAT6 AGRN AJUBA ANKS3 ATXN2 BECN1 BEGAIN BEND5 BRCA1 BRE CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3	38 interactors: ALS2CR11 ATXN1 BRCA1 CARM1 COIL FAM131C FAM214B FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 HSPA9 IFNGR2 INPP5J JAK2 KDM1A KRAS MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 RAD51 RASA1 RELA RNF34 SMAD9 STK16 TCF19 USP7 VHL ZBTB22
Entrez ID		8328	9093
HPRD ID		05088	09758
Ensembl ID		ENSG00000165702	ENSG00000103423
Uniprot IDs		Q5VTD9	B3KM81 E7ES32 Q53G26 Q59E88 Q96EY1
PDB IDs			2CTT 2DN9
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Cell Communication Regulation Of Cellular Component Organization Regulation Of Signaling Extracellular Matrix Organization Extracellular Structure Organization Signaling Cellular Response To Stimulus Signal Transduction Response To Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Regulation Of Growth Negative Regulation Of Wnt Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Canonical Wnt Signaling Pathway Developmental Process Secretion Negative Regulation Of Signaling Regulation Of Locomotion Cellular Process Regulation Of Cellular Component Movement Focal Adhesion Assembly Protein Localization Protein Ubiquitination Cellular Localization Negative Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Cell-substrate Adhesion Adherens Junction Assembly Cell Differentiation Cellular Component Assembly Neurogenesis Auditory Receptor Cell Fate Commitment Anatomical Structure Development Regulation Of Gene Expression Regulation Of Proteolysis Regulation Of Apoptotic Process Cell-substrate Junction Assembly Regulation Of I-kappaB Kinase/NF-kappaB Signaling Secretion By Cell Regulation Of Cell Proliferation Receptor Clustering Regulation Of Vesicle-mediated Transport	Response To Abiotic Stimulus Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Apoptotic Process Response To Organic Substance Response To Organonitrogen Compound Response To Stress Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Cellular Process Cellular Response To Stress Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Viral Process Positive Regulation Of NF-kappaB Transcription Factor Activity Transcription, DNA-templated Regulation Of Signaling RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Histone H3-R2 Methylation Response To Organic Cyclic Compound Response To Radiation Regulation Of Histone H3-K4 Methylation Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation Cellular Response To Organonitrogen Compound Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Stimulus Response To Temperature Stimulus
Tagcloud ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	acted adenocarcinoma allylamino causing cochaperone colony concluded conversely counteracting counterparts demethoxy differently egfr enhancing geldanamycin hsp70 hsp90 interacted inversely isoforms oncogenic orthotropic proteasomal restored subcutaneous tid1 ubiquitinylation xenograft
Tagcloud (Difference) ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	acted adenocarcinoma allylamino causing cochaperone colony concluded conversely counteracting counterparts demethoxy differently egfr enhancing geldanamycin hsp70 hsp90 interacted inversely isoforms oncogenic orthotropic proteasomal restored subcutaneous tid1 ubiquitinylation xenograft
Tagcloud (Intersection) ?