GFI1B and FBLN5

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GFI1B	FBLN5
Gene Name		growth factor independent 1B transcription repressor	fibulin 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nuclear Matrix	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Elastic Fiber
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Protein Binding Metal Ion Binding	Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Proliferation Chromatin Modification Hemopoiesis Regulation Of Histone H3-K4 Methylation	Regulation Of Cell Growth Cell-matrix Adhesion Extracellular Matrix Organization Protein Localization To Cell Surface Secretion Elastic Fiber Assembly Regulation Of Removal Of Superoxide Radicals
Pathways			Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		71 interactors: ACTN1 AES AGPAT6 AGRN AJUBA ANKS3 ATXN2 BECN1 BEGAIN BEND5 BRCA1 BRE CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3	7 interactors: ATN1 GFI1B LOXL1 LPA PAXIP1 SOD3 TOP3B
Entrez ID		8328	10516
HPRD ID		05088	05204
Ensembl ID		ENSG00000165702	ENSG00000140092
Uniprot IDs		Q5VTD9	Q9UBX5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Cell Communication Regulation Of Cellular Component Organization Regulation Of Signaling Extracellular Matrix Organization Extracellular Structure Organization Signaling Cellular Response To Stimulus Signal Transduction Response To Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Regulation Of Growth Negative Regulation Of Wnt Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Canonical Wnt Signaling Pathway Developmental Process Secretion Negative Regulation Of Signaling Regulation Of Locomotion Cellular Process Regulation Of Cellular Component Movement Focal Adhesion Assembly Protein Localization Protein Ubiquitination Cellular Localization Negative Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Cell-substrate Adhesion Adherens Junction Assembly Cell Differentiation Cellular Component Assembly Neurogenesis Auditory Receptor Cell Fate Commitment Anatomical Structure Development Regulation Of Gene Expression Regulation Of Proteolysis Regulation Of Apoptotic Process Cell-substrate Junction Assembly Regulation Of I-kappaB Kinase/NF-kappaB Signaling Secretion By Cell Regulation Of Cell Proliferation Receptor Clustering Regulation Of Vesicle-mediated Transport	Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Positive Regulation Of Histone H3-K36 Methylation Protein Deamination Regulation Of Histone Modification Regulation Of Chromosome Organization
Tagcloud ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation
Tagcloud (Difference) ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation
Tagcloud (Intersection) ?