GFI1B and KIF17

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GFI1B	KIF17
Gene Name		growth factor independent 1B transcription repressor	kinesin family member 17
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nuclear Matrix	Cytosol Kinesin Complex Microtubule Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Primary Cilium Periciliary Membrane Compartment
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Protein Binding Metal Ion Binding	ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Proliferation Chromatin Modification Hemopoiesis Regulation Of Histone H3-K4 Methylation	Organelle Organization Microtubule-based Movement Metabolic Process Protein Transport Vesicle-mediated Transport Neurogenesis Cell Projection Organization Protein Complex Localization
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		71 interactors: ACTN1 AES AGPAT6 AGRN AJUBA ANKS3 ATXN2 BECN1 BEGAIN BEND5 BRCA1 BRE CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3	7 interactors: APBA1 C16orf70 FHL5 GFI1B MAP3K10 MAP3K11 XPO1
Entrez ID		8328	57576
HPRD ID		05088	10388
Ensembl ID		ENSG00000165702	ENSG00000117245
Uniprot IDs		Q5VTD9	Q9P2E2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Cell Communication Regulation Of Cellular Component Organization Regulation Of Signaling Extracellular Matrix Organization Extracellular Structure Organization Signaling Cellular Response To Stimulus Signal Transduction Response To Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Regulation Of Growth Negative Regulation Of Wnt Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Canonical Wnt Signaling Pathway Developmental Process Secretion Negative Regulation Of Signaling Regulation Of Locomotion Cellular Process Regulation Of Cellular Component Movement Focal Adhesion Assembly Protein Localization Protein Ubiquitination Cellular Localization Negative Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Cell-substrate Adhesion Adherens Junction Assembly Cell Differentiation Cellular Component Assembly Neurogenesis Auditory Receptor Cell Fate Commitment Anatomical Structure Development Regulation Of Gene Expression Regulation Of Proteolysis Regulation Of Apoptotic Process Cell-substrate Junction Assembly Regulation Of I-kappaB Kinase/NF-kappaB Signaling Secretion By Cell Regulation Of Cell Proliferation Receptor Clustering Regulation Of Vesicle-mediated Transport	Activation Of JNKK Activity Activation Of JUN Kinase Activity Activation Of MAPKK Activity Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of JNK Cascade Ribosomal Small Subunit Export From Nucleus Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Metabolic Process Gamma-aminobutyric Acid Secretion Regulation Of Metabolic Process Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity MAPK Cascade Negative Regulation Of Transcription, DNA-templated Ribosomal Large Subunit Export From Nucleus Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Activation Of Protein Kinase Activity Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Ribosomal Subunit Export From Nucleus Gamma-aminobutyric Acid Transport Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Regulation Of Histone H3-K4 Methylation Positive Regulation Of Kinase Activity Glutamate Secretion Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transferase Activity Protein Export From Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Centrosome Duplication Positive Regulation Of Cell Death
Tagcloud ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	calmodulin camk cargo compartments complexity confinement conversely dendrites dendritic distances dramatically exits kinesin locally mobile nascent processed regimes restricts scales secretory segments spatial spatially tight trafficking transported tuned zones
Tagcloud (Difference) ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	calmodulin camk cargo compartments complexity confinement conversely dendrites dendritic distances dramatically exits kinesin locally mobile nascent processed regimes restricts scales secretory segments spatial spatially tight trafficking transported tuned zones
Tagcloud (Intersection) ?