GFI1B and LAMB1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GFI1B	LAMB1
Gene Name		growth factor independent 1B transcription repressor	laminin, beta 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nuclear Matrix	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-2 Complex Extracellular Space Extracellular Matrix Laminin-8 Complex Laminin-10 Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Protein Binding Metal Ion Binding	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Enzyme Binding Glycosphingolipid Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Proliferation Chromatin Modification Hemopoiesis Regulation Of Histone H3-K4 Methylation	Cell Adhesion Negative Regulation Of Cell Adhesion Axon Guidance Embryo Implantation Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration Extracellular Matrix Disassembly Extracellular Matrix Organization Positive Regulation Of Cell Migration Neuron Projection Development Substrate Adhesion-dependent Cell Spreading Endodermal Cell Differentiation Odontogenesis Positive Regulation Of Epithelial Cell Proliferation
Pathways			Axon guidance Laminin interactions ECM proteoglycans L1CAM interactions Non-integrin membrane-ECM interactions Degradation of the extracellular matrix
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691) Ulcerative colitis ( 19915572 20228799 19122664)
Protein-Protein Interactions		71 interactors: ACTN1 AES AGPAT6 AGRN AJUBA ANKS3 ATXN2 BECN1 BEGAIN BEND5 BRCA1 BRE CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3	10 interactors: ACHE ANTXR2 ATXN7 ATXN7L2 CACNA1A COL6A1 EIF3I ERBB2IP GFI1B TGFB1
Entrez ID		8328	3912
HPRD ID		05088	01029
Ensembl ID		ENSG00000165702	ENSG00000091136
Uniprot IDs		Q5VTD9	P07942 Q8TAS6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Cell Communication Regulation Of Cellular Component Organization Regulation Of Signaling Extracellular Matrix Organization Extracellular Structure Organization Signaling Cellular Response To Stimulus Signal Transduction Response To Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Regulation Of Growth Negative Regulation Of Wnt Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Canonical Wnt Signaling Pathway Developmental Process Secretion Negative Regulation Of Signaling Regulation Of Locomotion Cellular Process Regulation Of Cellular Component Movement Focal Adhesion Assembly Protein Localization Protein Ubiquitination Cellular Localization Negative Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Cell-substrate Adhesion Adherens Junction Assembly Cell Differentiation Cellular Component Assembly Neurogenesis Auditory Receptor Cell Fate Commitment Anatomical Structure Development Regulation Of Gene Expression Regulation Of Proteolysis Regulation Of Apoptotic Process Cell-substrate Junction Assembly Regulation Of I-kappaB Kinase/NF-kappaB Signaling Secretion By Cell Regulation Of Cell Proliferation Receptor Clustering Regulation Of Vesicle-mediated Transport	Cell Growth Neurotransmitter Metabolic Process Ossification Cellular Component Assembly Regulation Of Protein Secretion Cerebellar Molecular Layer Development Negative Regulation Of Synaptic Transmission, Cholinergic Neurotransmitter Receptor Biosynthetic Process Defense Response To Fungus, Incompatible Interaction Positive Regulation Of NAD+ ADP-ribosyltransferase Activity Synapse Assembly Receptor Metabolic Process Endoderm Development Cell Adhesion Growth Acetylcholine Catabolic Process Vestibular Nucleus Development Basal Protein Localization Active Induction Of Host Immune Response By Virus Acetylcholine Catabolic Process In Synaptic Cleft Regulation Of Histone Modification Negative Regulation Of Hyaluronan Biosynthetic Process Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Macrophage Derived Foam Cell Differentiation Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Neurotransmitter Levels Osteoblast Differentiation Regulation Of Protein Transport Regulation Of Secretion Negative Regulation Of Macrophage Cytokine Production Ossification Involved In Bone Remodeling Tolerance Induction To Self Antigen Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Exit From Mitosis Gamma-aminobutyric Acid Secretion Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization ERBB Signaling Pathway Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Receptor Biosynthetic Process Regulation Of Extracellular Matrix Assembly Positive Regulation Of Smooth Muscle Cell Differentiation Frontal Suture Morphogenesis Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Acetylcholine Secretion, Neurotransmission Synapse Organization Cell Morphogenesis Involved In Differentiation
Tagcloud ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	acad amp analogs boylan chambon cyclic dhss dhss2 dnase electrophoretic endoderm enhancer f9 flanking gudas homeobox hypersensitive laminin lohnes maximally natl parietal proc ra taneja teratocarcinoma transcriptionally transfections ttattaaca
Tagcloud (Difference) ?		appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge	acad amp analogs boylan chambon cyclic dhss dhss2 dnase electrophoretic endoderm enhancer f9 flanking gudas homeobox hypersensitive laminin lohnes maximally natl parietal proc ra taneja teratocarcinoma transcriptionally transfections ttattaaca
Tagcloud (Intersection) ?