BLOC1S6 and PLEKHA5

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		BLOC1S6	PLEKHA5
Description		biogenesis of lysosomal organelles complex 1 subunit 6	pleckstrin homology domain containing A5
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex Presynapse Axon Cytoplasm	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Anterograde Axonal Transport Synaptic Vesicle Docking Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation	Biological_process Reproductive System Development
Pathways		Golgi Associated Vesicle Biogenesis	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Thalamus volume ( 31530798)
Interacting Genes		38 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 CCDC136 CCDC22 CCHCR1 CDK5R1 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 KRT13 LURAP1 MED21 NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 SKA1 SLC4A1 SMN2 SNAPIN STX11 STX12 SYCE3 TPM3 WASHC3	36 interacting genes: ADK ARHGEF9 BET1 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 H2AJ KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 RECQL SH3BP5L SOGA1 SPIRE1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG
Entrez ID		26258	54477
HPRD ID		16055	09684
Ensembl ID		ENSG00000104164	ENSG00000052126
Uniprot IDs		B3KY40 H3BST1 Q9UL45	A0A024RAY7 Q9HAU0
PDB IDs			2DKP
Enriched GO Terms of Interacting Partners?
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