PLEKHA5 and CCDC92

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		PLEKHA5	CCDC92
Description		pleckstrin homology domain containing A5	coiled-coil domain containing 92
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse	Nucleoplasm Cytoplasm Centrosome Centriole Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding
	Biological Process	Biological_process Reproductive System Development
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Thalamus volume ( 31530798)	Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778 28714974) Hand grip strength ( 29691431) HDL cholesterol ( 20686565) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Metabolite levels ( 23823483) Reticulocyte count ( 27863252) Triglycerides ( 20686565) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference variance ( 31453325) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500) White blood cell count ( 27863252)
Interacting Genes		36 interacting genes: ADK ARHGEF9 BET1 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 H2AJ KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 RECQL SH3BP5L SOGA1 SPIRE1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	10 interacting genes: CEP76 CHGB COG6 FHL2 GOLGA2 PLEKHA5 PSMD8 TP53BP2 TRIM27 UBC
Entrez ID		54477	80212
HPRD ID		09684	16919
Ensembl ID		ENSG00000052126	ENSG00000119242
Uniprot IDs		A0A024RAY7 Q9HAU0	Q53HC0
PDB IDs		2DKP
Enriched GO Terms of Interacting Partners?
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