PLEKHA5 and CCDC88B

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		PLEKHA5	CCDC88B
Description		pleckstrin homology domain containing A5	coiled-coil domain containing 88B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Microtubule Binding Dynein Light Intermediate Chain Binding
	Biological Process	Biological_process Reproductive System Development	Positive Regulation Of Cytokine Production Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Positive Regulation Of T Cell Proliferation Defense Response To Protozoan Positive Regulation Of T Cell Activation
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Thalamus volume ( 31530798)	Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233) Keratinocyte cancer (MTAG) ( 31174203) Leprosy ( 25642632) Medication use (thyroid preparations) ( 31015401) Primary biliary cholangitis ( 26394269) Primary sclerosing cholangitis ( 27992413) Sarcoidosis ( 22837380)
Interacting Genes		36 interacting genes: ADK ARHGEF9 BET1 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 H2AJ KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 RECQL SH3BP5L SOGA1 SPIRE1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	3 interacting genes: PBX2 PLEKHA5 SRPK2
Entrez ID		54477	283234
HPRD ID		09684	10986
Ensembl ID		ENSG00000052126	ENSG00000168071
Uniprot IDs		A0A024RAY7 Q9HAU0	A6NC98 B2RTU8
PDB IDs		2DKP
Enriched GO Terms of Interacting Partners?
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