PLEKHA5 and PLEKHA6

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		PLEKHA5	PLEKHA6
Description		pleckstrin homology domain containing A5	pleckstrin homology domain containing A6
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Biological_process Reproductive System Development
Pathways		Synthesis of PIPs at the plasma membrane	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Thalamus volume ( 31530798)	Palmitoleic acid (16:1n-7) levels ( 23362303) Plateletcrit ( 27863252) Prostate cancer ( 23535732) Regular attendance at a religious group ( 29970889) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		36 interacting genes: ADK ARHGEF9 BET1 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 H2AJ KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 RECQL SH3BP5L SOGA1 SPIRE1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	2 interacting genes: APOE PLEKHA5
Entrez ID		54477	22874
HPRD ID		09684	09685
Ensembl ID		ENSG00000052126	ENSG00000143850
Uniprot IDs		A0A024RAY7 Q9HAU0	Q9Y2H5
PDB IDs		2DKP	2D9Y 2YRY
Enriched GO Terms of Interacting Partners?
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