Search Results for: PTEN

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
MYL12A myosin light chain 12A
  • EPHA-mediated growth cone collapse
  • Sema4D induced cell migration and growth-cone collapse
  • Smooth Muscle Contraction
  • RHO GTPases activate PKNs
  • RHO GTPases activate CIT
  • RHO GTPases Activate ROCKs
  • RHO GTPases activate PAKs
  • RHO GTPases activate PAKs
  • Ephrin signaling
  • Smooth Muscle Contraction
  • 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID
MYO1B myosin IB
MYO1C myosin IC
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Regulation of actin dynamics for phagocytic cup formation
  • FCGR3A-mediated phagocytosis
MYO1D myosin ID
MYOF myoferlin
NACA nascent polypeptide associated complex subunit alpha
NCBP1 nuclear cap binding protein subunit 1
  • SLBP independent Processing of Histone Pre-mRNAs
  • Formation of RNA Pol II elongation complex
  • Formation of the Early Elongation Complex
  • Transport of the SLBP independent Mature mRNA
  • Transport of the SLBP Dependant Mature mRNA
  • Transport of Mature mRNA Derived from an Intronless Transcript
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • Formation of HIV elongation complex in the absence of HIV Tat
  • Formation of the HIV-1 Early Elongation Complex
  • Formation of HIV-1 elongation complex containing HIV-1 Tat
  • Abortive elongation of HIV-1 transcript in the absence of Tat
  • snRNP Assembly
  • RNA Polymerase II Pre-transcription Events
  • FGFR2 alternative splicing
  • RNA polymerase II transcribes snRNA genes
  • mRNA Capping
  • mRNA Splicing - Major Pathway
  • mRNA Splicing - Minor Pathway
  • mRNA 3'-end processing
  • Processing of Capped Intron-Containing Pre-mRNA
  • RNA Polymerase II Transcription Termination
  • SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
  • Processing of Intronless Pre-mRNAs
  • Signaling by FGFR2 IIIa TM
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
NCF1 neutrophil cytosolic factor 1
  • ROS and RNS production in phagocytes
  • Cross-presentation of particulate exogenous antigens (phagosomes)
  • Detoxification of Reactive Oxygen Species
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases Activate NADPH Oxidases
  • Dextromethorphan
  • Chronic granulomatous disease, including the following four diseases: X-linked CGD (gp91 phox CGD); p22phox deficiency (p22phox CGD); p47phox deficiency (p47phox CGD); p67phox deficiency (p67phox CGD)
NDFIP1 Nedd4 family interacting protein 1
NGB neuroglobin
  • Intracellular oxygen transport
NOP56 NOP56 ribonucleoprotein
  • Association of TriC/CCT with target proteins during biosynthesis
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
NOP58 NOP58 ribonucleoprotein
  • SUMOylation of RNA binding proteins
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
NPM3 nucleophosmin/nucleoplasmin 3
NUMB NUMB endocytic adaptor protein
  • Activated NOTCH1 Transmits Signal to the Nucleus
  • Recycling pathway of L1
  • Degradation of GLI1 by the proteasome
  • Hedgehog 'on' state
OSGIN1 oxidative stress induced growth inhibitor 1
OTUD3 OTU deubiquitinase 3
  • Ovarian tumor domain proteases
  • Regulation of PTEN stability and activity
PBK PDZ binding kinase
PBRM1 polybromo 1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
PCNA proliferating cell nuclear antigen
  • Translesion synthesis by REV1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Translesion Synthesis by POLH
  • Transcription of E2F targets under negative control by DREAM complex
  • Polymerase switching on the C-strand of the telomere
  • Processive synthesis on the C-strand of the telomere
  • Telomere C-strand (Lagging Strand) Synthesis
  • Removal of the Flap Intermediate from the C-strand
  • SUMOylation of DNA replication proteins
  • Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • PCNA-Dependent Long Patch Base Excision Repair
  • Translesion synthesis by POLK
  • Translesion synthesis by POLI
  • Termination of translesion DNA synthesis
  • HDR through Homologous Recombination (HRR)
  • Gap-filling DNA repair synthesis and ligation in GG-NER
  • Dual Incision in GG-NER
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • Polymerase switching
  • Removal of the Flap Intermediate
  • Processive synthesis on the lagging strand
  • G1/S-Specific Transcription
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Liothyronine
  • Acetylsalicylic acid
PDGFRB platelet derived growth factor receptor beta
  • PIP3 activates AKT signaling
  • Downstream signal transduction
  • Signaling by PDGF
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • RAF/MAP kinase cascade
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • Becaplermin
  • Sorafenib
  • Imatinib
  • Dasatinib
  • Sunitinib
  • XL999
  • XL820
  • Pazopanib
  • Midostaurin
  • Regorafenib
  • Nintedanib
  • Polaprezinc
  • Trapidil
  • Foreskin fibroblast (neonatal)
  • Fostamatinib
  • Erdafitinib
  • Pexidartinib
  • Ripretinib
  • Pralsetinib
  • Glioma

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