ARHGAP32 and GRAP

Data Source:
HPRD (in vitro)

		ARHGAP32	GRAP
Description		Rho GTPase activating protein 32	GRB2 related adaptor protein
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Fibrillar Center Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cell Cortex Endosome Membrane Postsynaptic Density Actin Cytoskeleton Dendritic Spine	Cytoplasm Cytosol Membrane Presynapse
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol Phosphate Binding	Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Ras Protein Signal Transduction Cell-cell Signaling Sensory Perception Of Sound
Pathways		Rho GTPase cycle	Signaling by SCF-KIT
Drugs
Diseases
GWAS		Intracranial aneurysm ( 30823506) Iris color (L* coordinate) ( 29109912) Macular thickness ( 30535121) Metabolite levels (5-HIAA) ( 23319000) Refractive error ( 32231278)	Copper levels ( 26025379)
Interacting Genes		33 interacting genes: ABI2 ATXN1 BCAR1 CAMK2N2 CDC42 CDH1 CDH2 CRK CRKL CTNNB1 DLG4 DZIP3 FYN GAB1 GAB2 GRAP GRB2 GRIN2A GRIN2B LHX2 MDFI MEGF10 NCK1 NCK2 NPHP1 NTRK1 PIK3R1 PLCG1 RAC1 RHOA SHC3 SRC TLE5	17 interacting genes: ARHGAP32 DPPA4 EPOR FASLG FYN GAB2 KHDRBS1 KIT LAT LCK PLCG1 RBPMS REL SHC1 SOS1 TOX TRIM21
Entrez ID		9743	10750
HPRD ID		12257	05062
Ensembl ID		ENSG00000134909	ENSG00000154016
Uniprot IDs		A7KAX9 Q86T64	I3L2P9 Q13588
PDB IDs		3IUG
Enriched GO Terms of Interacting Partners?
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