ARHGAP32 and LHX2

Data Source:
BioGRID (two hybrid)

		ARHGAP32	LHX2
Description		Rho GTPase activating protein 32	LIM homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Fibrillar Center Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cell Cortex Endosome Membrane Postsynaptic Density Actin Cytoskeleton Dendritic Spine	Chromatin Nucleus
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol Phosphate Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Regulation Of Transcription By RNA Polymerase II Neuron Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways		Rho GTPase cycle	Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Intracranial aneurysm ( 30823506) Iris color (L* coordinate) ( 29109912) Macular thickness ( 30535121) Metabolite levels (5-HIAA) ( 23319000) Refractive error ( 32231278)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Blond vs. brown/black hair color ( 30531825) Depression ( 29700475) Hair color ( 29662168) Mercury levels ( 26025379) Post-traumatic stress disorder ( 25456346) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Waist circumference ( 23966867)
Interacting Genes		33 interacting genes: ABI2 ATXN1 BCAR1 CAMK2N2 CDC42 CDH1 CDH2 CRK CRKL CTNNB1 DLG4 DZIP3 FYN GAB1 GAB2 GRAP GRB2 GRIN2A GRIN2B LHX2 MDFI MEGF10 NCK1 NCK2 NPHP1 NTRK1 PIK3R1 PLCG1 RAC1 RHOA SHC3 SRC TLE5	28 interacting genes: ANKS1A ARHGAP32 BEND2 CITED2 DNMT3L FLYWCH1 HOMER3 HOXC8 KHK LDB1 LGALSL LNX1 LONRF1 MORF4L1 MORN3 MSX1 OSMR PAX6 POU4F2 PPIL1 RLIM TCEANC TCP11L1 TLK1 TRAPPC2L UBTFL1 ZFP42 ZNF511
Entrez ID		9743	9355
HPRD ID		12257	04786
Ensembl ID		ENSG00000134909	ENSG00000106689
Uniprot IDs		A7KAX9 Q86T64	B3KNJ5 P50458
PDB IDs		3IUG
Enriched GO Terms of Interacting Partners?
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