GRAP and ARHGAP32

Data Source:
HPRD (in vitro)

		GRAP	ARHGAP32
Description		GRB2 related adaptor protein	Rho GTPase activating protein 32
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Presynapse	Golgi Membrane Fibrillar Center Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cell Cortex Endosome Membrane Postsynaptic Density Actin Cytoskeleton Dendritic Spine
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Ras Protein Signal Transduction Cell-cell Signaling Sensory Perception Of Sound	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Signaling by SCF-KIT	Rho GTPase cycle
Drugs
Diseases
GWAS		Copper levels ( 26025379)	Intracranial aneurysm ( 30823506) Iris color (L* coordinate) ( 29109912) Macular thickness ( 30535121) Metabolite levels (5-HIAA) ( 23319000) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: ARHGAP32 DPPA4 EPOR FASLG FYN GAB2 KHDRBS1 KIT LAT LCK PLCG1 RBPMS REL SHC1 SOS1 TOX TRIM21	33 interacting genes: ABI2 ATXN1 BCAR1 CAMK2N2 CDC42 CDH1 CDH2 CRK CRKL CTNNB1 DLG4 DZIP3 FYN GAB1 GAB2 GRAP GRB2 GRIN2A GRIN2B LHX2 MDFI MEGF10 NCK1 NCK2 NPHP1 NTRK1 PIK3R1 PLCG1 RAC1 RHOA SHC3 SRC TLE5
Entrez ID		10750	9743
HPRD ID		05062	12257
Ensembl ID		ENSG00000154016	ENSG00000134909
Uniprot IDs		I3L2P9 Q13588	A7KAX9 Q86T64
PDB IDs			3IUG
Enriched GO Terms of Interacting Partners?
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