RALGDS and CD68

Data Source:
BioGRID (two hybrid)

		RALGDS	CD68
Description		ral guanine nucleotide dissociation stimulator	CD68 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Brush Border	Lysosome Lysosomal Membrane Plasma Membrane Membrane Integral Component Of Membrane Late Endosome Membrane Azurophil Granule Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Regulator Activity	Protein Binding
	Biological Process	Ras Protein Signal Transduction Regulation Of Catalytic Activity	Inflammatory Response To Antigenic Stimulus Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Aging Cellular Response To Nutrient Levels Autocrine Signaling Neutrophil Degranulation Cellular Response To Lipopolysaccharide Establishment Of Protein Localization To Organelle Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
Pathways		p38MAPK events p38MAPK events RAF/MAP kinase cascade	Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels in cardiovascular risk ( 28369058)	Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) IgA levels ( 28628107) Metabolic syndrome ( 31589552) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278)
Interacting Genes		26 interacting genes: AFDN ARRB1 ARRB2 CD68 CNKSR1 CYSRT1 HOXA1 HRAS KRAS KRTAP10-8 LRPAP1 MAPK3 MRAS NF2 PDPK1 RAP1A RAP1B RAP1GAP RAP2A RAP2B RAPGEF2 RIN1 RIT1 RIT2 RRAS RRAS2	12 interacting genes: ADRB2 AGR2 AQP6 CLEC2D KTN1 MAL2 MUC1 PLEKHB2 RALGDS SGTB TMEM179B TOMM6
Entrez ID		5900	968
HPRD ID		03371	01093
Ensembl ID		ENSG00000160271	ENSG00000129226
Uniprot IDs		Q12967 Q8N4Y1	P34810
PDB IDs		1RAX 2B3A 2RGF 3KH0
Enriched GO Terms of Interacting Partners?
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