TMEM19 and CD3G

Data Source:
BioGRID (two hybrid)

		TMEM19	CD3G
Description		transmembrane protein 19	CD3g molecule
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Clathrin-coated Vesicle Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Complex Adaptor Activity T Cell Receptor Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process		Adaptive Immune Response Establishment Or Maintenance Of Cell Polarity Cell Surface Receptor Signaling Pathway Protein Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis T Cell Activation Positive Thymic T Cell Selection Regulation Of Immune Response T Cell Receptor Signaling Pathway Membrane Organization Protein-containing Complex Assembly Regulation Of Lymphocyte Apoptotic Process
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis PD-1 signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis
Drugs			Muromonab
Diseases
GWAS		Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		38 interacting genes: APOA5 AQP6 BSCL2 C10orf67 CD3G CD79A CNR2 CPLX4 CREB3 CREB3L1 ELOVL4 FAM210B FCER1G GJB1 GORAB GPR42 GPRC5D GPX8 HSD17B13 KASH5 LEPROTL1 LY6E MC4R MFSD14B PGRMC2 PIGP PTGES REEP4 RNF185 SERTM1 SLC7A1 SUSD6 TEX29 TLCD4 TMEM139 TMEM14B TMEM159 TMEM45A	14 interacting genes: CD3D CD3E EMP1 KTN1 LAT MAL PMP22 TMEM19 TMEM203 TMEM262 TMEM54 TRA TRB TRD
Entrez ID		55266	917
HPRD ID		15530	07037
Ensembl ID		ENSG00000139291	ENSG00000160654
Uniprot IDs		A0A024RBA1 Q96HH6	B0YIY5 P09693
PDB IDs			1SY6 6JXR
Enriched GO Terms of Interacting Partners?
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