TMEM19 and PTGES

Data Source:
BioGRID (two hybrid)

		TMEM19	PTGES
Description		transmembrane protein 19	prostaglandin E synthase
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane	Nuclear Envelope Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Glutathione Transferase Activity Glutathione Peroxidase Activity Prostaglandin-D Synthase Activity Protein Binding Glutathione Binding Prostaglandin-E Synthase Activity
	Biological Process		Prostaglandin Biosynthetic Process Acute Inflammatory Response Chronic Inflammatory Response Prostaglandin Metabolic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Organic Cyclic Compound Sensory Perception Of Pain Cyclooxygenase Pathway Regulation Of Fever Generation Positive Regulation Of Prostaglandin Secretion Response To Lipopolysaccharide Response To Retinoic Acid Response To Cytokine Regulation Of Inflammatory Response Response To Calcium Ion Cellular Oxidant Detoxification
Pathways			Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS		Nonsyndromic cleft lip with cleft palate ( 28232668)	Asthma ( 27611488) Pars orbitalis volume ( 31530798)
Interacting Genes		38 interacting genes: APOA5 AQP6 BSCL2 C10orf67 CD3G CD79A CNR2 CPLX4 CREB3 CREB3L1 ELOVL4 FAM210B FCER1G GJB1 GORAB GPR42 GPRC5D GPX8 HSD17B13 KASH5 LEPROTL1 LY6E MC4R MFSD14B PGRMC2 PIGP PTGES REEP4 RNF185 SERTM1 SLC7A1 SUSD6 TEX29 TLCD4 TMEM139 TMEM14B TMEM159 TMEM45A	18 interacting genes: BET1 C4orf3 EHHADH GIMAP1 GIMAP5 PLP2 PTGER1 PTGER2 SEC22A SERP2 SMCO4 TMEM19 TMEM222 TMEM65 VAMP3 VAMP4 VAPB YIF1A
Entrez ID		55266	9536
HPRD ID		15530	05528
Ensembl ID		ENSG00000139291	ENSG00000148344
Uniprot IDs		A0A024RBA1 Q96HH6	O14684
PDB IDs			3DWW 4AL0 4AL1 4BPM 4WAB 4YK5 4YL0 4YL1 4YL3 5BQG 5BQH 5BQI 5K0I 5T36 5T37 5TL9
Enriched GO Terms of Interacting Partners?
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