AIMP1 and TSNAX

Data Source:
BioGRID (two hybrid)

		AIMP1	TSNAX
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 1	translin associated factor X
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GO Annotations	Cellular Component	Extracellular Space Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Cell Surface Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	TRNA Binding Cytokine Activity Protein Binding Protein Homodimerization Activity GTPase Binding	DNA Binding RNA Binding Endoribonuclease Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation TRNA Aminoacylation For Protein Translation Apoptotic Process Inflammatory Response Signal Transduction Cell-cell Signaling Leukocyte Migration Defense Response To Virus Positive Regulation Of Glucagon Secretion	Multicellular Organism Development Spermatogenesis Cell Differentiation Production Of SiRNA Involved In RNA Interference RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Small interfering RNA (siRNA) biogenesis
Drugs
Diseases		Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS			Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Metabolite levels ( 23823483)
Interacting Genes		50 interacting genes: AIMP2 APP ATP5F1A HOMER1 IQGAP1 MAPK14 MAPK8 MIR106B MIR107 MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR15A MIR15B MIR17 MIR199A1 MIR199A2 MIR19B1 MIR19B2 MIR205 MIR206 MIR20B MIR214 MIR222 MIR25 MIR29C MIR31 MIR34A MIR34B MIR34C MIR451A MIR7-1 MIR7-2 MIR7-3 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I OPTN RARS1 SUMO2 TSNAX	41 interacting genes: AIMP1 AKAP9 BEX3 BLOC1S5 C1D CARD9 CDK5RAP2 CEP68 CKAP4 COG6 EMILIN1 GADD45G GOLGA3 GPATCH2 GRIPAP1 HMGB2 KCNE4 KLC3 KRT31 LDB2 LDOC1 LZTS2 MRFAP1L1 NSMCE2 NTAQ1 PBXIP1 PMF1 PRPF18 RALYL RFC5 SOGA1 SPRED2 SUN1 SYCE2 SYT17 TCF12 TCP11L1 TSN TSNAXIP1 UBE2I VPS28
Entrez ID		9255	7257
HPRD ID		04676	04270
Ensembl ID		ENSG00000164022	ENSG00000116918
Uniprot IDs		B4DNK3 Q12904	A0A024R3V8 Q99598
PDB IDs		1E7Z 1EUJ 1FL0 4R3Z	3PJA 3QB5
Enriched GO Terms of Interacting Partners?
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