AIMP1 and ATP5F1A

Data Source:
HPRD (in vivo, in vitro)

		AIMP1	ATP5F1A
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 1	ATP synthase F1 subunit alpha
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Cell Surface Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Plasma Membrane COP9 Signalosome Membrane Proton-transporting ATP Synthase Complex Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Exosome
	Molecular Function	TRNA Binding Cytokine Activity Protein Binding Protein Homodimerization Activity GTPase Binding	RNA Binding Protein Binding ATP Binding ATPase Activity MHC Class I Protein Binding ADP Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation TRNA Aminoacylation For Protein Translation Apoptotic Process Inflammatory Response Signal Transduction Cell-cell Signaling Leukocyte Migration Defense Response To Virus Positive Regulation Of Glucagon Secretion	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Mitochondrial protein import Formation of ATP by chemiosmotic coupling Cristae formation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Artenimol
Diseases		Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Interacting Genes		50 interacting genes: AIMP2 APP ATP5F1A HOMER1 IQGAP1 MAPK14 MAPK8 MIR106B MIR107 MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR15A MIR15B MIR17 MIR199A1 MIR199A2 MIR19B1 MIR19B2 MIR205 MIR206 MIR20B MIR214 MIR222 MIR25 MIR29C MIR31 MIR34A MIR34B MIR34C MIR451A MIR7-1 MIR7-2 MIR7-3 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I OPTN RARS1 SUMO2 TSNAX	18 interacting genes: ABCC1 AIMP1 APP ATP5F1C ATPAF2 CSNK2A1 HSD17B10 HSPB2 LINC01554 NPSR1 PTEN PTPRF SHBG SMARCB1 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		9255	498
HPRD ID		04676	01258
Ensembl ID		ENSG00000164022	ENSG00000152234
Uniprot IDs		B4DNK3 Q12904	P25705 V9HW26
PDB IDs		1E7Z 1EUJ 1FL0 4R3Z
Enriched GO Terms of Interacting Partners?
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