CD6 and GYG1

Data Source:
BioGRID (two hybrid)

		CD6	GYG1
Description		CD6 molecule	glycogenin 1
Image
GO Annotations	Cellular Component	Immunological Synapse Extracellular Region Integral Component Of Plasma Membrane External Side Of Plasma Membrane Intrinsic Component Of Plasma Membrane T Cell Receptor Complex	Extracellular Region Cytosol Membrane Secretory Granule Lumen Lysosomal Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Lipopolysaccharide Binding Scavenger Receptor Activity Protein Binding Identical Protein Binding Lipoteichoic Acid Binding	Protein Binding Glycogenin Glucosyltransferase Activity Transferase Activity, Transferring Glycosyl Groups Manganese Ion Binding Protein Homodimerization Activity UDP-alpha-D-glucose:glucosyl-glycogenin Alpha-D-glucosyltransferase Activity
	Biological Process	Immunological Synapse Formation Adaptive Immune Response Acute Inflammatory Response To Antigenic Stimulus Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of T Cell Proliferation Innate Immune Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Glycogen Biosynthetic Process Neutrophil Degranulation
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1) Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)
Drugs			Uridine diphosphate glucose Uridine-5'-Diphosphate
Diseases
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Multiple sclerosis ( 31604244 21244703 24076602 19525953 21833088) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Diverticular disease ( 30177863)
Interacting Genes		5 interacting genes: ALCAM CD5 GYG1 NFE2L1 SDCBP	7 interacting genes: C1QTNF9 CD6 CMSS1 GYG2 GYS1 POM121 TRIM7
Entrez ID		923	2992
HPRD ID		01724	06805
Ensembl ID		ENSG00000013725	ENSG00000163754
Uniprot IDs		P30203 Q6AZ88 Q8N4Q7	P46976
PDB IDs		5A2E	3Q4S 3QVB 3RMV 3RMW 3T7M 3T7N 3T7O 3U2T 3U2U 3U2V 3U2W 3U2X 6EQJ 6EQL
Enriched GO Terms of Interacting Partners?
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