GYG1 and GYS1

Data Source:
HPRD (two hybrid)

		GYG1	GYS1
Description		glycogenin 1	glycogen synthase 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Membrane Secretory Granule Lumen Lysosomal Lumen Ficolin-1-rich Granule Lumen	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Protein Binding Glycogenin Glucosyltransferase Activity Transferase Activity, Transferring Glycosyl Groups Manganese Ion Binding Protein Homodimerization Activity UDP-alpha-D-glucose:glucosyl-glycogenin Alpha-D-glucosyltransferase Activity	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Glycogen Biosynthetic Process Neutrophil Degranulation	Glycogen Biosynthetic Process Heart Development
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1) Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)	Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs		Uridine diphosphate glucose Uridine-5'-Diphosphate
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Diverticular disease ( 30177863)
Interacting Genes		7 interacting genes: C1QTNF9 CD6 CMSS1 GYG2 GYS1 POM121 TRIM7	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		2992	2997
HPRD ID		06805	00721
Ensembl ID		ENSG00000163754	ENSG00000104812
Uniprot IDs		P46976	P13807
PDB IDs		3Q4S 3QVB 3RMV 3RMW 3T7M 3T7N 3T7O 3U2T 3U2U 3U2V 3U2W 3U2X 6EQJ 6EQL
Enriched GO Terms of Interacting Partners?
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