GYG1 and CD6

Data Source:
BioGRID (two hybrid)

		GYG1	CD6
Description		glycogenin 1	CD6 molecule
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Membrane Secretory Granule Lumen Lysosomal Lumen Ficolin-1-rich Granule Lumen	Immunological Synapse Extracellular Region Integral Component Of Plasma Membrane External Side Of Plasma Membrane Intrinsic Component Of Plasma Membrane T Cell Receptor Complex
	Molecular Function	Protein Binding Glycogenin Glucosyltransferase Activity Transferase Activity, Transferring Glycosyl Groups Manganese Ion Binding Protein Homodimerization Activity UDP-alpha-D-glucose:glucosyl-glycogenin Alpha-D-glucosyltransferase Activity	Lipopolysaccharide Binding Scavenger Receptor Activity Protein Binding Identical Protein Binding Lipoteichoic Acid Binding
	Biological Process	Glycogen Biosynthetic Process Neutrophil Degranulation	Immunological Synapse Formation Adaptive Immune Response Acute Inflammatory Response To Antigenic Stimulus Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of T Cell Proliferation Innate Immune Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1) Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)
Drugs		Uridine diphosphate glucose Uridine-5'-Diphosphate
Diseases
GWAS		Diverticular disease ( 30177863)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Multiple sclerosis ( 31604244 21244703 24076602 19525953 21833088) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		7 interacting genes: C1QTNF9 CD6 CMSS1 GYG2 GYS1 POM121 TRIM7	5 interacting genes: ALCAM CD5 GYG1 NFE2L1 SDCBP
Entrez ID		2992	923
HPRD ID		06805	01724
Ensembl ID		ENSG00000163754	ENSG00000013725
Uniprot IDs		P46976	P30203 Q6AZ88 Q8N4Q7
PDB IDs		3Q4S 3QVB 3RMV 3RMW 3T7M 3T7N 3T7O 3U2T 3U2U 3U2V 3U2W 3U2X 6EQJ 6EQL	5A2E
Enriched GO Terms of Interacting Partners?
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