REPS2 and RALBP1

Data Source:
HPRD (in vitro, two hybrid)

		REPS2	RALBP1
Description		RALBP1 associated Eps domain containing 2	ralA binding protein 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Cytosol Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	GTPase Activator Activity Protein Binding Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Endosomal Transport Membrane Organization Protein-containing Complex Assembly	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Rho GTPase cycle
Drugs
Diseases
GWAS			LDL cholesterol ( 30275531)
Interacting Genes		13 interacting genes: AR ASAP1 ASAP2 CDK1 CDK5RAP2 EPN1 EPS15 GRB2 PXN RALB RALBP1 RELA REPS1	44 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		9185	10928
HPRD ID		02262	09013
Ensembl ID		ENSG00000169891	ENSG00000017797
Uniprot IDs		Q8NFH8	Q15311
PDB IDs		1IQ3	2KWH 2KWI 2MBG
Enriched GO Terms of Interacting Partners?
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