REPS2 and ASAP2

		REPS2	ASAP2
Description		RALBP1 associated Eps domain containing 2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Plasma Membrane Golgi Cisterna Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Endosomal Transport Membrane Organization Protein-containing Complex Assembly	Positive Regulation Of GTPase Activity
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic obstructive pulmonary disease ( 30804561) Pulse pressure ( 27841878 30578418) Urate levels ( 31578528)
Interacting Genes		13 interacting genes: AR ASAP1 ASAP2 CDK1 CDK5RAP2 EPN1 EPS15 GRB2 PXN RALB RALBP1 RELA REPS1	14 interacting genes: APC ARF1 ARF5 ARF6 BIN1 GRB2 ITSN1 PACSIN3 PTK2B PXN RAN REPS2 SH3KBP1 THSD7A
Entrez ID		9185	8853
HPRD ID		02262	04820
Ensembl ID		ENSG00000169891	ENSG00000151693
Uniprot IDs		Q8NFH8	O43150
PDB IDs		1IQ3
Enriched GO Terms of Interacting Partners?
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