EIF2B2 and MRFAP1L1

Data Source:
BioGRID (two hybrid)

		EIF2B2	MRFAP1L1
Description		eukaryotic translation initiation factor 2B subunit beta	Morf4 family associated protein 1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding GTP Binding	Protein Binding Identical Protein Binding
	Biological Process	Ovarian Follicle Development Translational Initiation Regulation Of Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways		Recycling of eIF2:GDP
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Coronary artery disease ( 33020668) Mood instability ( 29187730) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		12 interacting genes: APP C9orf72 CCT3 CSNK2A2 EIF2B1 EIF2B4 EIF2B5 EIF2S1 MRFAP1L1 NCK1 PCGF6 TET2	46 interacting genes: ABI1 ABI2 ABI3 BYSL C1orf216 C3orf62 CAGE1 CAVIN3 CDK2AP1 CDK2AP2 CENPK CEP44 CNOT7 CSPP1 EIF2B2 GAS8 GTF2IRD1 HGS HTT IHO1 LMO2 LNX1 LNX2 MEOX2 MORF4L1 MORF4L2 MRFAP1 NTAQ1 PIH1D2 PIK3R2 PSMA1 RADIL RDM1 SDCBP SFR1 SMARCE1 SMU1 SYCE1 TCF4 TEX11 TMEM126B TSNAX TXN2 UBTD1 ZDHHC17 ZNF417
Entrez ID		8892	114932
HPRD ID		05923	15162
Ensembl ID		ENSG00000119718	ENSG00000178988
Uniprot IDs		P49770 Q53XC2	A0A075DDR2 Q96HT8
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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