ACTL6A and FLII

Data Source:
HPRD (in vivo)

		ACTL6A	FLII
Description		actin like 6A	FLII actin remodeling protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Plasma Membrane SWI/SNF Complex Ino80 Complex Protein-containing Complex NuA4 Histone Acetyltransferase Complex NpBAF Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Brush Border Focal Adhesion Actin Cytoskeleton Centriolar Satellite
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process	Blastocyst Formation Neural Retina Development DNA Repair DNA Recombination Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Signal Transduction Nervous System Development Protein Deubiquitination Spinal Cord Development Regulation Of Growth ATP-dependent Chromatin Remodeling Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated	Multicellular Organism Development Actin Polymerization Or Depolymerization Myofibril Assembly Actin Filament Severing Barbed-end Actin Filament Capping
Pathways		HATs acetylate histones RMTs methylate histone arginines UCH proteinases DNA Damage Recognition in GG-NER RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Pars opercularis volume ( 31530798)
Interacting Genes		14 interacting genes: ARHGDIA CDK2 CDK9 EWSR1 FLII MRGBP MYC POLR2A PTEN RELA RUVBL1 SMARCA2 SMARCA4 TRRAP	13 interacting genes: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MYD88 NCOA2 OPTN PRMT1 TRAIP
Entrez ID		86	2314
HPRD ID		05389	02647
Ensembl ID		ENSG00000136518	ENSG00000177731
Uniprot IDs		O96019	Q13045
PDB IDs		6LTJ
Enriched GO Terms of Interacting Partners?
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