FLII and GRIP1

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		FLII	GRIP1
Description		FLII actin remodeling protein	glutamate receptor interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Brush Border Focal Adhesion Actin Cytoskeleton Centriolar Satellite	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	Protein Binding Beta-catenin Binding Protein C-terminus Binding Signaling Receptor Complex Adaptor Activity Glucocorticoid Receptor Binding
	Biological Process	Multicellular Organism Development Actin Polymerization Or Depolymerization Myofibril Assembly Actin Filament Severing Barbed-end Actin Filament Capping	Dendrite Development Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization
Pathways			Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS			Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		13 interacting genes: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MYD88 NCOA2 OPTN PRMT1 TRAIP	42 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH
Entrez ID		2314	23426
HPRD ID		02647	19086
Ensembl ID		ENSG00000177731	ENSG00000155974
Uniprot IDs		Q13045	Q9Y3R0
PDB IDs			2JIL
Enriched GO Terms of Interacting Partners?
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