ACTL6A and MRGBP

Data Source:
HPRD (in vitro)

		ACTL6A	MRGBP
Description		actin like 6A	MRG domain binding protein
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Plasma Membrane SWI/SNF Complex Ino80 Complex Protein-containing Complex NuA4 Histone Acetyltransferase Complex NpBAF Complex	Nucleoplasm NuA4 Histone Acetyltransferase Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding	Protein Binding
	Biological Process	Blastocyst Formation Neural Retina Development DNA Repair DNA Recombination Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Signal Transduction Nervous System Development Protein Deubiquitination Spinal Cord Development Regulation Of Growth ATP-dependent Chromatin Remodeling Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Histone Acetylation Regulation Of Growth
Pathways		HATs acetylate histones RMTs methylate histone arginines UCH proteinases DNA Damage Recognition in GG-NER RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	HATs acetylate histones
Drugs
Diseases
GWAS		Pars opercularis volume ( 31530798)
Interacting Genes		14 interacting genes: ARHGDIA CDK2 CDK9 EWSR1 FLII MRGBP MYC POLR2A PTEN RELA RUVBL1 SMARCA2 SMARCA4 TRRAP	25 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP1-1 KRTAP10-7 KRTAP17-1 KRTAP5-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NBPF19 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4
Entrez ID		86	55257
HPRD ID		05389	16646
Ensembl ID		ENSG00000136518	ENSG00000101189
Uniprot IDs		O96019	Q9NV56
PDB IDs		6LTJ	2N1D
Enriched GO Terms of Interacting Partners?
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